GRIA2

Gene Symbol	GRIA2
Entrez Gene	2891
Alt Symbol	GLUR2, GLURB, GluA2, GluR-K2, HBGR2
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, ionotropic, AMPA 2
Other Description	AMPA-selective glutamate receptor 2|gluR-2|gluR-B|glutamate receptor 2
Swissprots	A8MT92 I6L997 Q96FP6 P42262
Accessions	AAF23955 EAX04865 EAX04866 EAX04867 EAX04868 EAX04869 EAX04870 EAX04871 P42262 AB209567 BAD92804 AK294458 BAH11774 AK308775 AK309067 AL708924 AL832605 BC010574 AAH10574 BC028736 AAH28736 BP202382 BP202686 DA228330 DA810082 FJ460423 ACJ74177 FJ460424 ACJ74178 FJ460425 ACJ74179 FJ460426 ACJ74180 FJ460427 ACJ74181 FJ460428 ACJ74182 FJ460429 ACJ74183 FJ460430 ACJ74184 FJ460431 ACJ74185 FJ460432 ACJ74186 JN547408 AEQ93812 L20814 AAA58631 X64829 X64830 XM_011531892 XP_011530194 XR_938725 NM_000826 NP_000817 NM_001083619 NP_001077088 NM_001083620 NP_001077089
Function	Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. {ECO:0000269|PubMed:20614889}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:23739980}; Multi-pass membrane protein {ECO:0000269|PubMed:23739980}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000269|PubMed:23739980}; Multi-pass membrane protein {ECO:0000269|PubMed:23739980}. Note=Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression. {ECO:0000250}.
Top Pathways	Amphetamine addiction, cAMP signaling pathway, Circadian entrainment, Cocaine addiction, Retrograde endocannabinoid signaling

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat GRIA2 / GLUR2 ELISA Kit (Cell-Based ELISA) - LS-F2018 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.313-20 ng/ml

Mouse/Human/Rat Phospho-GRIA2 / GLUR2 (Ser880) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1519 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.313-20 ng/ml

Human GRIA2 / GLUR2 ELISA Kit (Sandwich ELISA) - LS-F8851 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.115 ng/ml Range 0.313-20 ng/ml

Mouse GRIA2 / GLUR2 ELISA Kit (Sandwich ELISA) - LS-F8852 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.061 ng/ml Range 0.313-20 ng/ml

Human GRIA2 ELISA Kit - abx151739 from Abbexa Category ELISA Kit Sensitivity 0.115 ng/ml Range 0.313 ng/ml - 20 ng/ml

Glutamate receptor 2 (GRIA2), Human, ELISA Kit - E01G0391 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Glutamate Receptor, Ionotropic, AMPA 2, ELISA Kit - MBS078012 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate Receptor, Ionotropic, AMPA 2, ELISA Kit - MBS087230 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate Receptor, Ionotropic, AMPA 2, ELISA Kit - MBS073407 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate Receptor, Ionotropic, AMPA 2, ELISA Kit - MBS072141 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

GluR2 Colorimetric Cell-Based ELISA Kit - CB5296 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

GluR2 (Phospho-Ser880) Colorimetric Cell-Based ELISA Kit - CBP1565 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7214866 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7245352 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7252014 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7203645 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7244118 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7248223 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7248480 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7230840 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7207046 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7238029 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7252695 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate receptor 2 (GRIA2), ELISA Kit - MBS7206881 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Glutamate Receptor, Ionotropic, AMPA 2, ELISA Kit - MBS066032 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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