Gene Symbol | ALOX5AP |
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Entrez Gene | 241 |
Alt Symbol | FLAP |
Species | Human |
Gene Type | protein-coding |
Description | arachidonate 5-lipoxygenase-activating protein |
Other Description | MK-886-binding protein |
Swissprots | Q5VV04 P20292 |
Accessions | AAA35845 AAT38104 EAX08467 P20292 AK314143 BC018538 AAH18538 BG569867 BQ003388 DQ891647 ABM82573 DQ894836 ABM85762 XM_011535024 XP_011533326 XM_011535025 XP_011533327 NM_001204406 NP_001191335 NM_001629 NP_001620 |
Function | Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. {ECO:0000269|PubMed:2300173, ECO:0000269|PubMed:8440384}. |
Subcellular Location | Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Human FLAP full length protein - ab114639 from Abcam
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Human FLAP peptide - ab98291 from Abcam
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ALOX5AP / FLAP Antibody Blocking Peptide - LS-E25734 from LifeSpan Bioscience
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ALOX5AP / FLAP Antibody Blocking Peptide - LS-E26175 from LifeSpan Bioscience
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ALOX5AP / FLAP Antibody Blocking Peptide - LS-E9356 from LifeSpan Bioscience
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Recombinant Human FLAP Protein - H00000241-P01 from Novus Biologicals
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ALOX5AP-Antibody-Center-Blocking-Peptide - BP7897c from Abgent, a WuXi AppTec company
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ALOX5AP-Antibody-C-term-Blocking-Peptide - BP7897b from Abgent, a WuXi AppTec company
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FLAP (C Term) blocking peptide - GTX89725-PEP from GeneTex
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FLAP (internal) blocking peptide - GTX89246-PEP from GeneTex
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Human ALOX5AP His tag protein - orb83721 from Biorbyt
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FLAP Peptide - AC21-0563-P from Abcore
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FLAP Peptide - AC21-1006-P from Abcore
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ALOX5AP / FLAP - H00000241-P01-02 from Acris Antibodies
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ALOX5AP / FLAP Control Peptide - AP05297CP-N from Acris Antibodies
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ALOX5AP Peptide - 45-241P from ProSci
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ALOX5AP Peptide - 45-242P from ProSci
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ALOX5AP fusion protein - ag3144 from Proteintech Group
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Recombinant Human ALOX5AP, His tagged - ALOX5AP-3336H from Creative Biomart
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FLAP - PN201595 from Elabscience
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Human ALOX5AP / FLAP Protein (His Tag) - 11623-H08B-20 from Sino Biological
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ALOX5AP Peptide (OEEG01158) - OEEG01158 from Aviva Systems Biology
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FLAP Peptide - abx165206 from Abbexa
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ALOX5AP / FLAP - TP303785 from Acris Antibodies
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Arachidonate 5-lipoxygenase-activating protein (ALOX5AP), Recombinant Protein - MBS956958 from MyBioSource
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