ALOX5AP

Gene Symbol ALOX5AP
Entrez Gene 241
Alt Symbol FLAP
Species Human
Gene Type protein-coding
Description arachidonate 5-lipoxygenase-activating protein
Other Description MK-886-binding protein
Swissprots Q5VV04 P20292
Accessions AAA35845 AAT38104 EAX08467 P20292 AK314143 BC018538 AAH18538 BG569867 BQ003388 DQ891647 ABM82573 DQ894836 ABM85762 XM_011535024 XP_011533326 XM_011535025 XP_011533327 NM_001204406 NP_001191335 NM_001629 NP_001620
Function Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. {ECO:0000269|PubMed:2300173, ECO:0000269|PubMed:8440384}.
Subcellular Location Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

FLAP (FL-161) - sc-28815 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FLAP (FL-161): sc-28815. Western blot analysis of FLAP expression in LADMAC whole cell lysate.

FLAP (M-17) - sc-18187 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FLAP (T-19) - sc-18186 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FLAP antibody - ab53536 from Abcam

Prices $384.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-FLAP antibody (ab53536) at 0.1 µg/ml + Human U937 cell lysate (35µg protein in RIPA buffer).

Anti-FLAP antibody - ab85227 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FLAP antibody (ab85227) at 1 µg/mlLane 1 : U937 (Human leukemic monocyte lymphoma cell line) Whole Cell LysateLane 2 : THP1 (Human acute monocytic leukemia cell line) Whole Cell LysateLane 3 : Small Intestine (Human) Tissue Lysate - adult normal tissue (ab29276)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-FLAP antibody - ab80222 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-FLAP antibody (ab80222) at 1/50 dilution + K562 cell line lysate at 35 µg

Anti-FLAP antibody - ab151515 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-FLAP antibody (ab151515) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-FLAP antibody - ab39535 from Abcam

Prices $372.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-FLAP antibody [EPR5640] - ab124714 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5640
All lanes : Anti-FLAP antibody [EPR5640] (ab124714) at 1/1000 dilutionLane 1 : Raji cell lysatesLane 2 : THP1 cell lysatesLane 3 : HepG2 cell lysatesLane 4 : K562 cell lysatesLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-ALOX5AP / FLAP Antibody (Internal, clone EPR5640) - LS-C138786 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5640
Western blot analysis on (A) Raji, (B) THP-1, (C) HepG2, and (D) K562 cell lysates using anti-FLAP antibody.

Anti-ALOX5AP / FLAP Antibody - LS-C140591 from LifeSpan Bioscience

Prices $460.00
Sizes 10 blot
Host Rabbit
Clonality Polyclonal
Western blot of antigen immunoaffinity purified and FLAP antibody (LS-C140591) on human kidney cell lysate. Lysate used at 15 ug/lane. Antibody used at 5 ug/ml. Secondary antibody, mouse anti-rabbit HRP, used at 1:75k dilution. Visualized using Pierce West Femto substrate system. Exposure for 5 minutes

Anti-ALOX5AP / FLAP Antibody - LS-C140606 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of FLAP antibody (LS-C140606) on human kidney cell lysate. Lysate used at 15 ug/lane. Antibody used at 5 ug/ml. Secondary antibody, mouse anti-rabbit HRP, used at 1:25k dilution. Visualized using Pierce West Femto substrate system. Exposure for 5 minutes

Anti-ALOX5AP / FLAP Antibody (aa86-117) - LS-C99454 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-ALOX5AP / FLAP Antibody IHC-plus™ - LS-B4069 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-ALOX5AP / FLAP antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4069 concentration 10 ug/ml.

Anti-ALOX5AP / FLAP Antibody (aa148-161) IHC-plus™ - LS-B4971 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-ALOX5AP / FLAP antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4971 concentration 3.75 ug/ml.

Anti-ALOX5AP / FLAP Antibody (aa28-40) IHC-plus™ - LS-B4933 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-ALOX5AP / FLAP antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4933 concentration 3.75 ug/ml.

FLAP Antibody - NBP1-30984 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: FLAP Antibody [NBP1-30984] - Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE; antibody diluted at 1:1000.

FLAP Antibody - NB100-53797 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

FLAP Antibody - NBP1-84666 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FLAP Antibody [NBP1-84666] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

FLAP Antibody - NB300-891 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: FLAP Antibody [NB300-891] - Staining of FLAP using NB300-891 in primary mouse fibroblast cells at 1:500 dilution and counterstained with Hoechst dye. Image courtesy of Lidia Hernandez, NCI Center for Cancer Research

5-lipoxygenase activating protein Antibody - bs-7556R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit

Anti-ALOX5AP (center) antibody produced in rabbit - SAB1300959 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ALOX5AP (Center) Antibody: <B>Cat. No. SAB1300959</B>: ALOX5AP in human lung carcinoma tissue with Anti-ALOX5AP (Center) Antibody at 40 μg/mL.

Anti-ALOX5AP (31-45) antibody produced in rabbit - A0735 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-ALOX5AP (31-45): <B>Cat. No. A0735</B>: Immunofluorescence of HUVEC cells using ALOX5AP (31-45), Cat. No. A0735 (red) at a 1:100 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-FLAP/ALOX5AP, C-Terminal antibody produced in goat - SAB2500402 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ALOX5AP antibody produced in rabbit - HPA026592 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ALOX5AP: <B>Cat. No. HPA026592</B>: Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in lymphoid cells outside the reaction centra.
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