MRC2

Gene Symbol MRC2
Entrez Gene 9902
Alt Symbol CD280, CLEC13E, ENDO180, UPARAP
Species Human
Gene Type protein-coding
Description mannose receptor, C type 2
Other Description C-type lectin domain family 13 member E|C-type mannose receptor 2|UPAR-associated protein|endocytic receptor (macrophage mannose receptor family)|endocytic receptor 180|macrophage mannose receptor 2|urokinase-type plasminogen activator receptor-associated protein
Swissprots Q9Y5P9 Q7LGE7 D3DU08 A6H8K4 Q9UBG0
Accessions EAW94341 EAW94342 Q9UBG0 AB014609 BAA31684 AF107292 AAF14192 AF134838 AAD30280 AI458446 AK093230 BAG52674 AY429551 BC032763 BC146647 AAI46648 BC150212 AAI50213 BC153884 AAI53885 BX111813 U58856 AAC51365 XM_011525543 XP_011523845 XR_934628 NM_006039 NP_006030
Function May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs). {ECO:0000269|PubMed:10683150, ECO:0000269|PubMed:12972549}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Ubiquitous with low expression in brain, placenta, lung, kidney, pancreas, spleen, thymus and colon. Expressed in endothelial cells, fibroblasts and macrophages. Highly expressed in fetal lung and kidney. {ECO:0000269|PubMed:10683150, ECO:0000269|PubMed:8702911}.
Top Pathways Phagosome, Tuberculosis

Human MRC2 / Endo180 ELISA Kit (Sandwich ELISA) - LS-F7867 from LifeSpan Bioscience

Category ELISA Kit
Prices $650.00
Sizes 1 plate
Sensitivity 0.117 ng/ml
Range 0.313-20 ng/ml

Mouse MRC2 / Endo180 ELISA Kit (Sandwich ELISA) - LS-F7975 from LifeSpan Bioscience

Category ELISA Kit
Prices $670.00
Sizes 1 plate
Sensitivity 6.5 pg/ml
Range 0.313-20 ng/ml

Human MRC2 / Endo180 ELISA Kit (Sandwich ELISA) - LS-F12078 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.312
Range 0.313-20 ng/ml

Human MRC2 ELISA Kit - abx152380 from Abbexa

Category ELISA Kit
Sensitivity 0.117 ng/ml
Range 0.313 ng/ml - 20 ng/ml

C-type mannose receptor 2 (MRC2), Human, ELISA Kit - CSB-EL014784HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

C-type mannose receptor 2 (MRC2), Human, ELISA Kit - E01C2342 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

C-type mannose receptor 2, MRC2, Human, ELISA Kit - E2105h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t
Range 0.312-20 ng/mL

Mannose Receptor C Type 2 (MRC2), Human, ELISA Kit - SEA733Hu from ARP American Research Products

Category ELISA Kit
Prices $650.00
Sizes 96 t
Sensitivity 0.117ng/mL
Range 0.312-20ng/mL

Mannose Receptor C Type 2, MRC2, Human, ELISA Kit - E-EL-H2391 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.188
Range 0.313-20ng/mL

Mannose Receptor C Type 2, MRC2, Rabbit, ELISA Kit - E-EL-RB2228 from ARP American Research Products

Category ELISA Kit
Prices $648.00
Sizes 96 t

Mannose Receptor C Type 2, MRC2, Chicken, ELISA Kit - E-EL-Ch0466 from ARP American Research Products

Category ELISA Kit
Prices $504.00
Sizes 96 t

Mannose Receptor C Type 2, MRC2, Porcine, ELISA Kit - E-EL-P1887 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Mannose Receptor C Type 2, MRC2, Monkey, ELISA Kit - E-EL-MK0833 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7218996 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7248182 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7239067 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7228839 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7217595 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7221955 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7230167 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7228380 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7209952 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7236329 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-type mannose receptor 2 (MRC2), ELISA Kit - MBS7206650 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human MRC2(Mannose Receptor C Type 2) ELISA Kit - E-EL-H2391 from Elabscience

Category ELISA Kit
Sensitivity 0.19 ng/mL
Range 0.31—20 ng/mL
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