Gene Symbol | ANKRD2 |
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Entrez Gene | 26287 |
Alt Symbol | ARPP |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat domain 2 (stretch responsive muscle) |
Other Description | ankyrin repeat domain-containing protein 2|skeletal muscle ankyrin repeat protein |
Swissprots | Q70EZ9 Q3B778 Q96MG0 Q5T456 Q8WUD7 Q9GZV1 Q9NQC9 |
Accessions | CAC19411 EAW49916 EAW49917 Q9GZV1 AB058599 BAB60958 AJ249975 CAB99416 AJ304805 CAC19412 AJ346356 AJ583444 CAE47432 AK056990 AK314763 BAG37301 BC020817 AAH20817 BC107759 AAI07760 DA893829 NM_001129981 NP_001123453 NM_001291218 NP_001278147 NM_001291219 NP_001278148 NM_020349 NP_065082 |
Function | Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress. {ECO:0000269|PubMed:21737686, ECO:0000269|PubMed:22016770}. |
Subcellular Location | Cytoplasm, myofibril, sarcomere, I band {ECO:0000250}. Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Note=In the sarcoplasm of differentiated striated muscle cells, where it is cytosolic and enriched in the I band. In nucleus and PML bodies of proliferating and undifferentiated myoblasts. Associates with the euchromatin in the nucleus of myocytes upon muscle stress. |
Tissue Specificity | Mostly expressed in skeletal and cardiac muscles. Found in slow fibers. Also expressed in kidney, but to a lower extent (at protein level). {ECO:0000269|PubMed:11444853, ECO:0000269|PubMed:11453652}. |
ANKRD2 (A-14) - sc-138110 from Santa Cruz Biotechnology
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ANKRD2 (D-15) - sc-138111 from Santa Cruz Biotechnology
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Anti-ANKRD2 antibody - ab59694 from Abcam
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Anti-ANKRD2 antibody [EPR10730(B)] - ab156875 from Abcam
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Anti-ANKRD2 antibody [EPR10731(B)] - ab151718 from Abcam
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Anti-ANKRD2 antibody - C-terminal - ab192909 from Abcam
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Anti-ANKRD2 Antibody (aa51-100) - LS-C40393 from LifeSpan Bioscience
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Anti-ANKRD2 Antibody (C-Terminus) - LS-C345763 from LifeSpan Bioscience
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Anti-ANKRD2 Antibody (clone YAS11) IHC-plus⢠- LS-B11844 from LifeSpan Bioscience
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ANKRD2 Antibody - NBP1-91669 from Novus Biologicals
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ANKRD2 Antibody - NBP1-56443 from Novus Biologicals
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ANKRD2 Antibody - NBP1-91670 from Novus Biologicals
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Anti-ANKRD2 antibody produced in rabbit - HPA040884 from Sigma-Aldrich
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Anti-ANKRD2 antibody produced in rabbit - HPA040842 from Sigma-Aldrich
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Anti-ANKRD2 antibody produced in rabbit - AV42559 from Sigma-Aldrich
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ANKRD2 antibody - N-terminal region (ARP42559_P050) - ARP42559_P050 from Aviva Systems Biology
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ANKRD2 Antibody - C-terminal region (ARP74385_P050) - ARP74385_P050 from Aviva Systems Biology
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ANKRD2 antibody, N-term - GTX46994 from GeneTex
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Anti -ANKRD2 (Ankyrin Repeat Domain-containing Protein 2, ARPP) - 209514 from USBiological Life Science
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ANKRD2 antibody - 70R-15722 from Fitzgerald
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ANKRD2 Polyclonal Antibody - A4622 from ABclonal
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ANKRD2 antibody - 70R-3378 from Fitzgerald
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ANKRD2 Antibody - abx003476 from Abbexa
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Ankyrin Repeat Domain 2 (Stretch Responsive Muscle) Antibody - abx110989 from Abbexa
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ANKRD2 antibody - 11821-1-AP from Acris Antibodies
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