PDCD6

Gene Symbol PDCD6
Entrez Gene 10016
Alt Symbol ALG-2, ALG2, PEF1B
Species Human
Gene Type protein-coding
Description programmed cell death 6
Other Description apoptosis-linked gene 2 protein|probable calcium-binding protein ALG-2|programmed cell death protein 6
Swissprots O75340 B2RD16 E7ESR3 Q5TZS0 Q2YDC2
Accessions EAW50987 EAW50990 EAW50991 O75340 AF035606 AAC27697 AK001917 AK024175 AK124302 AK128087 BAC87267 AK223366 BAD97086 AK295082 BAG58124 AK308872 AK310347 AK315370 BAG37763 AW300963 BC012384 AAH12384 BC028242 BC050597 AAH50597 BC106706 AAI06707 BC110291 AAI10292 BG390506 BI553617 BT020072 AAV38875 CR983268 DB495449 DQ891163 ABM82089 DQ894344 ABM85270 U58773 AAF14336 NM_001267556 NP_001254485 NM_001267557 NP_001254486 NM_001267558 NP_001254487 NM_001267559 NP_001254488 NM_013232 NP_037364 NR_073609
Function Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5. {ECO:0000250, ECO:0000269|PubMed:16132846, ECO:0000269|PubMed:17889823, ECO:0000269|PubMed:19520058, ECO:0000269|PubMed:19864416, ECO:0000269|PubMed:21893193}.
Subcellular Location Nucleus membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus. Endosome. Note=Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus. Translocated from the cytoplasm to the nucleus after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.

Human PDCD6 / ALG-2 ELISA Kit (Sandwich ELISA) - LS-F7885 from LifeSpan Bioscience

Category ELISA Kit
Prices $790.00
Sizes 1 plate
Sensitivity 0.118 ng/ml
Range 0.313-20 ng/ml

Human PDCD6 ELISA Kit - abx152670 from Abbexa

Category ELISA Kit
Sensitivity 0.118 ng/ml
Range 0.313 ng/ml - 20 ng/ml

Programmed Cell Death Protein 6 (PDCD6), Human, ELISA Kit - SEL096Hu from ARP American Research Products

Category ELISA Kit
Prices $790.00
Sizes 96 t
Sensitivity 0.118ng/mL
Range 0.312-20ng/mL

Programmed Cell Death Protein 6, ELISA Kit - MBS094219 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS055589 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS068390 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS054592 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS075596 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS051020 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS049515 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS047729 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS049014 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS086154 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS053388 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS071056 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS086438 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS075178 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS081578 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS058037 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS093123 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS078532 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS084166 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS075719 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6, ELISA Kit - MBS059122 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 (PDCD6), ELISA Kit - MBS2021171 from MyBioSource

Category ELISA Kit
Prices $410.00, $610.00, $830.00, $3,420.00, $6,200.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.118ng/mL.
Range 0.313-20ng/mL
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