APOA1

Gene Symbol APOA1
Entrez Gene 335
Alt Symbol -
Species Human
Gene Type protein-coding
Description apolipoprotein A-I
Other Description apo-AI
Swissprots Q9UCT8 A8K866 P02647 Q9UCS8 Q6Q785 Q6LDN9
Accessions AAA51746 AAB59514 AAD34604 AAL92035 AAQ91811 AAS68227 ACA05932 ACA05933 ACA05934 ACA05935 ACA05936 AFU51373 CAA25519 CAA30377 EAW67274 EAW67275 EAW67276 EAW67277 P02647 A14829 CAA01198 A15879 CAA01253 AK292231 BAF84920 BC005380 AAH05380 BC110286 AAI10287 DQ893073 ABM83999 DQ896330 ABM87329 M11791 AAA35545 M27875 AAA62829 M29068 AAA51747 X00566 CAA25232 X02162 CAA26097 XM_005271539 XP_005271596 XM_005271540 XP_005271597 NM_000039 NP_000030
Function Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. {ECO:0000269|PubMed:1909888}.
Subcellular Location Secreted.
Tissue Specificity Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease. {ECO:0000269|PubMed:12576517}.
Top Pathways PPAR signaling pathway, African trypanosomiasis, Fat digestion and absorption, Vitamin digestion and absorption

ApoA1 (5F4) Mouse mAb - 3350 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 5F4
Western blot analysis of decreasing concentrations of ApoA1 protein purified from human serum using ApoA1 (5F4) Mouse mAb.

apoA-I (E-20) - sc-23605 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
apoA-I (E-20): sc-23605. Western blot analysis of apoA-I expression in non-transfected: sc-117752 (A) and mouse apoA-I transfected: sc-118477 (B) 293T whole cell lysates.

apoA-I (FL-267) - sc-30089 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
apoA-I (FL-267): sc-30089. Western blot analysis of apoA-I expression in human VLDL (A) and HDL (B).

apoA-I (B-10) - sc-376818 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
apoA-I (B-10): sc-376818. Immunofluorescence staining of formalin-fixed HepG2 cells showing golgi apparatus localization.

apoA-I (C-18) - sc-19029 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

apoA-I (G-11) - sc-376811 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
apoA-I (G-11): sc-376811. Immunofluorescence staining of formalin-fixed HepG2 cells showing golgi apparatus localization.

apoA-I (069-01) - sc-58230 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
apoA-I (069-01): sc-58230. Western blot analysis of apoA-I expression in HeLa whole cell lysate.

apoA-I (2G4) - sc-69755 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
apoA-I (2G4): sc-69755. Western blot analysis of apoA-I expression in non-transfected: sc-117752 (A) and mouse apoA-I transfected: sc-118477 (B) 293T whole cell lysates.

apoA-I (12C8) - sc-80551 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
apoA-I (12C8): sc-80551. Western blot analysis of apoA-I expression in non-transfected: sc-117752 (A) and human apoA-I transfected: sc-111827 (B) 293T whole cell lysates.

Anti-Apolipoprotein A I antibody - ab7613 from Abcam

Prices $394.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
IHC image of Apolipoprotein A I staining in human normal liver formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab7613, 1µg/ml, for 15 mins at room temperature. A donkey anti-goat biotinylated secondary antibody was used to detect the primary, and visualized using an HRP conjugated ABC system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Apolipoprotein A I antibody - ab64308 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Standard Curve for Apolipoprotein A I (Analyte: ab50239) dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal [1409] to Apolipoprotein A I (ab20918) at 1ug/ml and Detector Antibody Rabbit polyclonal to Apolipoprotein A I (ab64308) at 0.5ug/ml

Anti-Apolipoprotein A I antibody - ab191485 from Abcam

Prices $382.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Apolipoprotein A I antibody (ab191485) at 1/2000 dilutionLane 1 : HepG2 (Human liver hepatocellular carcinoma) cell lysateLane 2 : Rat liver lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-Apolipoprotein A I antibody - ab124424 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab124424, at 1/100 dilution, staining Apolipoprotein A I in formalin-fixed, paraffin-embedded Human liver tissue by Immunohistochemistry.

Anti-Apolipoprotein A I antibody - ab117311 from Abcam

Prices $378.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Human plasma Apolipoprotein A I protein as test antigen. ab117311 (0.1 ug/ml), and Rabbit anti-IgY-HRP as 2nd antibody

Anti-Apolipoprotein A I antibody - ab169831 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Apolipoprotein A I antibody (ab169831) at 0.5 µg/ml + Human liver lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-Apolipoprotein A I antibody - ab157415 from Abcam

Prices $370.00
Sizes 150 µg
Host Chicken
Clonality Polyclonal

Anti-Apolipoprotein A I antibody - ab33470 from Abcam

Prices $372.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-Apolipoprotein A I antibody [10H10] - ab63867 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10H10

Anti-Apolipoprotein A I antibody [12C8] - ab17278 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 12C8
All lanes : Anti-Apolipoprotein A I antibody [12C8] (ab17278) at 5 µg/mlLane 1 : Ovary (Human) Tissue Lysate - adult normal tissue (ab30222)Lane 2 : Lung (Human) Tissue Lysate Lysates/proteins at 10 µg per lane.SecondaryLane 1 : Goat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionLane 2 : Goat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Anti-Apolipoprotein A I antibody [1402] - ab20411 from Abcam

Prices $370.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 1402

Anti-Apolipoprotein A I antibody [1405] - ab20735 from Abcam

Prices $370.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone 1405

Anti-Apolipoprotein A I antibody [1409] - ab20918 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1409
Standard Curve for Apolipoprotein A I (Analyte: ab50239) dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal [1409] to Apolipoprotein A I (ab20918) at 1ug/ml and Detector Antibody Rabbit polyclonal to Apolipoprotein A I (ab64308) at 0.5ug/ml

Anti-Apolipoprotein A I antibody [1C5] - ab63864 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C5

Anti-Apolipoprotein A I antibody [532] - ab116599 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 532

Anti-Apolipoprotein A I antibody [6A9G6,5F4F5] - ab66334 from Abcam

Host Mouse
Clonality Monoclonal
Clone 6A9G6,5F4F5
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