Gene Symbol | GRIK1 |
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Entrez Gene | 2897 |
Alt Symbol | EAA3, EEA3, GLR5, GLUR5, GluK1 |
Species | Human |
Gene Type | protein-coding |
Description | glutamate receptor, ionotropic, kainate 1 |
Other Description | excitatory amino acid receptor 3|gluR-5|glutamate receptor 5|glutamate receptor ionotropic, kainate 1 |
Swissprots | Q13001 Q86SU9 P39086 |
Accessions | AAD03059 AAD04931 BAA97452 EAX09906 EAX09907 EAX09908 EAX09909 EAX09910 P39086 AA404271 AJ249208 CAC80546 AK294353 BAH11742 AK296404 BAH12343 BC028238 BC039447 BC111793 BC152727 AAI52728 BC156975 AAI56976 L19058 AAA52568 U16125 AAA95961 XM_005260942 XP_005260999 XM_005260943 XP_005261000 XM_005260944 XP_005261001 XM_006723991 XP_006724054 XM_011529527 XP_011527829 XM_011529528 XP_011527830 NM_000830 NP_000821 NM_175611 NP_783300 |
Function | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Most abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus. |
Top Pathways | Glutamatergic synapse, Neuroactive ligand-receptor interaction |
Mouse/Human/Rat GRIK1 / GLUR5 ELISA Kit (Cell-Based ELISA) - LS-F2020 from LifeSpan Bioscience
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Glutamate receptor, ionotropic kainate 1 (GRIK1), Human, ELISA Kit - E01G0396 from ARP American Research Products
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GluR5 Colorimetric Cell-Based ELISA Kit - CB5298 from Assay Biotechnology
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glutamate receptor (NMDAR) , ELISA Kit - MBS2602961 from MyBioSource
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GluR5 ELISA Kit - DEIA-XYA743 from Creative Diagnostics
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Human GRIK1 ELISA Kit - E016744 from Biobool
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anti-GLuR5 / GRIK1 antibody - ARG55272 from Arigo Biolaboratories
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glutamate receptor (NMDAR), ELISA Kit - MBS2610478 from MyBioSource
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GluR5 Colorimetric Cell-Based ELISA Kit - EKA50255 from Biomatik
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