Gene Symbol | GRIK1 |
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Entrez Gene | 2897 |
Alt Symbol | EAA3, EEA3, GLR5, GLUR5, GluK1 |
Species | Human |
Gene Type | protein-coding |
Description | glutamate receptor, ionotropic, kainate 1 |
Other Description | excitatory amino acid receptor 3|gluR-5|glutamate receptor 5|glutamate receptor ionotropic, kainate 1 |
Swissprots | Q13001 Q86SU9 P39086 |
Accessions | AAD03059 AAD04931 BAA97452 EAX09906 EAX09907 EAX09908 EAX09909 EAX09910 P39086 AA404271 AJ249208 CAC80546 AK294353 BAH11742 AK296404 BAH12343 BC028238 BC039447 BC111793 BC152727 AAI52728 BC156975 AAI56976 L19058 AAA52568 U16125 AAA95961 XM_005260942 XP_005260999 XM_005260943 XP_005261000 XM_005260944 XP_005261001 XM_006723991 XP_006724054 XM_011529527 XP_011527829 XM_011529528 XP_011527830 NM_000830 NP_000821 NM_175611 NP_783300 |
Function | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Most abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus. |
Top Pathways | Glutamatergic synapse, Neuroactive ligand-receptor interaction |
GRIK1 peptide - ab115358 from Abcam
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Human GRIK1 protein fragment - ab116734 from Abcam
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GRIK1 / GLUR5 Antibody Blocking Peptide - LS-E30412 from LifeSpan Bioscience
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GRIK1 / GLUR5 Antibody Blocking Peptide - LS-E30413 from LifeSpan Bioscience
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GRIK1 / GLUR5 Antibody Blocking Peptide - LS-E26447 from LifeSpan Bioscience
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Recombinant Human GluR5/GRIK1 Protein - H00002897-Q01 from Novus Biologicals
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GluR5/GRIK1 Blocking Peptide - NBP1-76850PEP from Novus Biologicals
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GluR5/GRIK1 Blocking Peptide - NBP1-76849PEP from Novus Biologicals
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GRIK1 blocking peptide - GTX88972-PEP from GeneTex
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GRIK1 Peptide - AC21-1286-P from Abcore
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Glutamate receptor 5 / GLUR5 - H00002897-Q01-10 from Acris Antibodies
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Glutamate receptor 5 / GLUR5 - H00002897-Q01-25 from Acris Antibodies
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Glutamate receptor 5 / GLUR5 Control Peptide - AP30380CP-N from Acris Antibodies
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Glutamate receptor 5 / GLUR5 Control Peptide - AP30381CP-N from Acris Antibodies
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GLuR5 Peptide - 45-679P from ProSci
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Grik1 Peptide - 4383P from ProSci
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Grik1 Peptide - 4381P from ProSci
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Recombinant Human GRIK1 - GRIK1-28537TH from Creative Biomart
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GluR-5 (L12) Peptide - BS1145P from Bioworld Technology
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GLuR5/GRIK1, Peptide - MBS425589 from MyBioSource
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GRIK1 Peptide, Human - M34GP06653H from Creative Peptides
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Glutamate Receptor, Recombinant Protein - MBS2029065 from MyBioSource
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Glutamate Receptor, Recombinant Protein - MBS2028845 from MyBioSource
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Glutamate Receptor, Recombinant Protein - MBS2029706 from MyBioSource
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Glutamate Receptor, Recombinant Protein - MBS2028984 from MyBioSource
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