GRIK1

Gene Symbol GRIK1
Entrez Gene 2897
Alt Symbol EAA3, EEA3, GLR5, GLUR5, GluK1
Species Human
Gene Type protein-coding
Description glutamate receptor, ionotropic, kainate 1
Other Description excitatory amino acid receptor 3|gluR-5|glutamate receptor 5|glutamate receptor ionotropic, kainate 1
Swissprots Q13001 Q86SU9 P39086
Accessions AAD03059 AAD04931 BAA97452 EAX09906 EAX09907 EAX09908 EAX09909 EAX09910 P39086 AA404271 AJ249208 CAC80546 AK294353 BAH11742 AK296404 BAH12343 BC028238 BC039447 BC111793 BC152727 AAI52728 BC156975 AAI56976 L19058 AAA52568 U16125 AAA95961 XM_005260942 XP_005260999 XM_005260943 XP_005261000 XM_005260944 XP_005261001 XM_006723991 XP_006724054 XM_011529527 XP_011527829 XM_011529528 XP_011527830 NM_000830 NP_000821 NM_175611 NP_783300
Function Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Tissue Specificity Most abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus.
Top Pathways Glutamatergic synapse, Neuroactive ligand-receptor interaction

GluR-5 (H-50) - sc-28798 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GluR-5 (H-50): sc-28798. Western blot analysis of human recombinant GluR-5 fusion protein.

GluR-5 (N-19) - sc-7617 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GluR-5 (V-17) - sc-26473 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GluR-5 (C-18) - sc-7616 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GluR-5 (C-18): sc-7616. Immunoperoxidase staining of formalin fixed, paraffin-embedded human upper stomach tissue showing cytoplasmic staining of glandular cells.

GluR-5 (E-12) - sc-393420 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GluR-5 (E-12): sc-393420. Western blot analysis of GluR-5 expression in mouse brain tissue extract.

GluR-5 (Q-19) - sc-26475 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GluR-5/6/7 (M-270) - sc-28797 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GluR-5/6/7 (M-270): sc-28797. Western blot analysis of GluR-5/6/7 expression in HeLa (A), A-431 (B), Jurkat (C), A549 (D) and U-251-MG (E) whole cell lysates.

Anti-GluR 5 + 6 + 7 antibody [2Q57] - ab64704 from Abcam

Host Mouse
Clonality Monoclonal
Clone 2Q57

Anti-GluR 5 + 6 + 7 antibody [4F5] - ab77739 from Abcam

Prices $359.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4F5
ab77739 staining adult monkey pyramidal cells.

Anti-GRIK1 antibody - ab67317 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-GRIK1 antibody (ab67317) at 0.5 µg/mlLane 2 : Anti-GRIK1 antibody (ab67317) at 1 µg/mlLane 1 : rat brain tissue lysateLane 2 : rat brain tissue lysateLysates/proteins at 15 µg per lane.

Anti-GRIK1 antibody - ab67316 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-GRIK1 antibody (ab67316) at 0.5 µg/mlLane 2 : Anti-GRIK1 antibody (ab67316) at 1 µg/mlLane 3 : Anti-GRIK1 antibody (ab67316) at 2 µg/mlLane 1 : P815 cell lysateLane 2 : P815 cell lysateLane 3 : P815 cell lysateLysates/proteins at 15 µg per lane.

Anti-GRIK1 antibody - ab118891 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab118891 at 5 &microg/ml staining GRIK1 in Formalin-fixed, Paraffin-embedded Human Adrenal tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-GRIK1 / GLUR5 Antibody (Leu12) - LS-C176040 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of GluR5 (L12) pAb in paraffin-embedded human brain tissue.

Anti-GRIK1 / GLUR5 Antibody (aa271-450) - LS-C344060 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
GRIK1 antibody Western blot. All lanes: Anti GRIK1 at 0.5 ug/ml. Lane 1: Mouse Brain Tissue Lysate at 50 ug. Lane 2: Mouse Brain Tissue Lysate at 50 ug. Lane 3: SHG Whole Cell Lysate at 40 ug. Predicted band size: 104 kD. Observed band size: 104 kD.

Anti-GRIK1 / GLUR5 Antibody (C-Terminus) IHC-plus™ - LS-B2691 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GRIK1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2691 concentration 5 ug/ml.

Anti-GRIK1 / GLUR5 Antibody (Internal) IHC-plus™ - LS-B2692 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GRIK1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2692 concentration 5 ug/ml.

Anti-GRIK1 / GLUR5 Antibody (aa878-889) IHC-plus™ - LS-B8298 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-GRIK1 / GLUR5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8298 dilution 3.75 ug/ml.

Anti-GRIK1 / GLUR5 Antibody (aa937-949) - LS-C15374 from LifeSpan Bioscience

Prices $530.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-GRIK1 / GLUR5 Antibody (C-Terminus) - LS-C41931 from LifeSpan Bioscience

Prices $395.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-GRIK1 / GLUR5 Antibody (aa10-59) - LS-C118465 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain tissue, using GluR5 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-GRIK1 / GLUR5 Antibody - LS-C152936 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
IHC: Mouse anti-GluR (LS-C152936) staining of adult monkey pyramidal cells

Anti-GRIK1 / GLUR5 Antibody (aa131-180) - LS-C205663 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GRIK1 / GLUR5 antibody Western Blot of Mouse Thymus. Antibody dilution: 1 ug/ml.

GluR5/GRIK1 Antibody - NB100-91785 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GluR5/GRIK1 Antibody [NB100-91785] - Glutamate Receptor 5 Antibody [NB100-91785] - Lane1:HEK293T whole cell lysate. Lane2:Mouse liver tissue lysate. Lane3:Rat liver tissue lysate.

GluR5/GRIK1 Antibody - NBP1-76850 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GluR5/GRIK1 Antibody [NBP1-76850] - Rt brain tissue lysate with Glutamate receptor 5 antibody at (A) 0.5 and (B) 1 ug/ml.

GluR5/GRIK1 Antibody - NBP1-76849 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GluR5/GRIK1 Antibody [NBP1-76849] - P815 cell lysate with Glutamate receptor 5 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
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