ZFYVE19

Gene Symbol	ZFYVE19
Entrez Gene	84936
Alt Symbol	ANCHR, MPFYVE
Species	Human
Gene Type	protein-coding
Description	zinc finger, FYVE domain containing 19
Other Description	MLL partner containing FYVE domain|abscission/NoCut checkpoint regulator|zinc finger FYVE domain-containing protein 19
Swissprots	Q8WU96 Q86WC2 H3BUF9 Q96K21 B3KVB2 C9JNF4
Accessions	EAW92447 EAW92448 EAW92449 EAW92450 EAW92451 EAW92452 EAW92453 EAW92454 EAW92455 Q96K21 AB209224 BAD92461 AF445414 AAO73862 AK027746 BAB55338 AK122779 BAG53724 AK225553 BC015738 BC021092 AAH21092 BI860679 DA611931 DA653225 DB012963 DQ575146 XR_931925 NM_001077268 NP_001070736 NM_001258420 NP_001245349 NM_001258421 NP_001245350 NM_032850 NP_116239
Function	Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission. {ECO:0000269|PubMed:24814515}.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:24814515}. Cleavage furrow {ECO:0000269|PubMed:24814515}. Midbody {ECO:0000269|PubMed:24814515}. Note=Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis (PubMed:24814515). {ECO:0000269|PubMed:24814515}.
Tissue Specificity	Detected in brain, heart, skeletal muscle, kidney and liver. {ECO:0000269|PubMed:12618766}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ZFYVE19 (D-14) - sc-165939 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

ZFYVE19 (E-14) - sc-165940 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

ZFYVE19 (T-16) - sc-165941 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

ZFYVE19 (J-24) - sc-101051 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-ZFYVE19 antibody - ab110471 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 antibody - ab155331 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 antibody - ab81418 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 antibody [EPR9789] - ab155085 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR9789

Anti-ZFYVE19 Antibody (aa387-415, APC) - LS-C274031 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa387-415, AP) - LS-C274032 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa387-415, Biotin) - LS-C274033 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa387-415, FITC) - LS-C274034 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa387-415, Azide-free, HRP) - LS-C274035 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa387-415, PE) - LS-C274036 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa425-471) - LS-C288588 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa375-425) - LS-C288587 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa386-415) - LS-C326498 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa1-397, clone GtxHu, Azide-free) - LS-C329151 from LifeSpan Bioscience Prices $485.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone GtxHu

Anti-ZFYVE19 Antibody (C-Terminus) - LS-C81550 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa311-360) - LS-C120476 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (aa387-415) - LS-C160787 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ZFYVE19 Antibody (clone 3G4-2B11) - LS-C139515 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3G4-2B11

ZFYVE19 Antibody (4D5-2D11) - H00084936-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 4D5-2D11

ZFYVE19 Antibody - NBP2-20951 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ZFYVE19 Antibody - H00084936-B01 from Novus Biologicals Prices $349.00 Sizes 50 µl Host Mouse Clonality Polyclonal

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