ZFYVE19

Gene Symbol	ZFYVE19
Entrez Gene	84936
Alt Symbol	ANCHR, MPFYVE
Species	Human
Gene Type	protein-coding
Description	zinc finger, FYVE domain containing 19
Other Description	MLL partner containing FYVE domain|abscission/NoCut checkpoint regulator|zinc finger FYVE domain-containing protein 19
Swissprots	Q8WU96 Q86WC2 H3BUF9 Q96K21 B3KVB2 C9JNF4
Accessions	EAW92447 EAW92448 EAW92449 EAW92450 EAW92451 EAW92452 EAW92453 EAW92454 EAW92455 Q96K21 AB209224 BAD92461 AF445414 AAO73862 AK027746 BAB55338 AK122779 BAG53724 AK225553 BC015738 BC021092 AAH21092 BI860679 DA611931 DA653225 DB012963 DQ575146 XR_931925 NM_001077268 NP_001070736 NM_001258420 NP_001245349 NM_001258421 NP_001245350 NM_032850 NP_116239
Function	Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission. {ECO:0000269|PubMed:24814515}.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:24814515}. Cleavage furrow {ECO:0000269|PubMed:24814515}. Midbody {ECO:0000269|PubMed:24814515}. Note=Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis (PubMed:24814515). {ECO:0000269|PubMed:24814515}.
Tissue Specificity	Detected in brain, heart, skeletal muscle, kidney and liver. {ECO:0000269|PubMed:12618766}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ZFYVE19 protein fragment - ab127349 from Abcam Category Protein Source E. coli Species Human

ZFYVE19 Antibody Blocking Peptide - LS-E2125 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZFYVE19 Antibody Blocking Peptide - LS-E18215 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ZFYVE19 Protein - H00084936-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ZFYVE19-Antibody-C-term-Blocking-peptide - BP13027b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ZFYVE19 Blocking Peptide - 33R-1752 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ZFYVE19 - H00084936-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ZFYVE19 - H00084936-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ZFYVE19 fusion protein - Ag19593 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

ZFYVE19 fusion protein - ag19627 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human ZFYVE19, GST-tagged - ZFYVE19-3805H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Zinc finger FYVE domain-containing protein 19(ZFYVE19) - CSB-YP853444HU CSB-EP853444HU CSB-BP853444HU CSB-MP853444HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ZFYVE19 - TP313044 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Zinc finger FYVE domain-containing protein 19 (ZFYVE19) , Recombinant Protein - MBS1389044 from MyBioSource Category Protein Prices $2,045.00, $2,045.00, $2,510.00, $2,510.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ZFYVE19 Blocking Peptide - abx061119 from Abbexa Category Peptide Species Human

ZFYVE19 Recombinant Protein Antigen - NBP1-83679PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZFYVE19 Peptide, Human - M34GP17814H from Creative Peptides Category Peptide Source Synthetic. Species Human

ZFYVE19 Blocking Peptide - CBP5032 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

ZFYVE19 peptide - orb319178 from Biorbyt Category Peptide

Recombinant Human ZFYVE19 Protein, His-tagged - ZFYVE19-309H from Creative Biomart Category Protein Source E. coli Species Human

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