ZFYVE19

Gene Symbol ZFYVE19
Entrez Gene 84936
Alt Symbol ANCHR, MPFYVE
Species Human
Gene Type protein-coding
Description zinc finger, FYVE domain containing 19
Other Description MLL partner containing FYVE domain|abscission/NoCut checkpoint regulator|zinc finger FYVE domain-containing protein 19
Swissprots Q8WU96 Q86WC2 H3BUF9 Q96K21 B3KVB2 C9JNF4
Accessions EAW92447 EAW92448 EAW92449 EAW92450 EAW92451 EAW92452 EAW92453 EAW92454 EAW92455 Q96K21 AB209224 BAD92461 AF445414 AAO73862 AK027746 BAB55338 AK122779 BAG53724 AK225553 BC015738 BC021092 AAH21092 BI860679 DA611931 DA653225 DB012963 DQ575146 XR_931925 NM_001077268 NP_001070736 NM_001258420 NP_001245349 NM_001258421 NP_001245350 NM_032850 NP_116239
Function Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission. {ECO:0000269|PubMed:24814515}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:24814515}. Cleavage furrow {ECO:0000269|PubMed:24814515}. Midbody {ECO:0000269|PubMed:24814515}. Note=Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis (PubMed:24814515). {ECO:0000269|PubMed:24814515}.
Tissue Specificity Detected in brain, heart, skeletal muscle, kidney and liver. {ECO:0000269|PubMed:12618766}.

ZFYVE19 CRISPR/Cas9 KO Plasmid (h) - sc-413741 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE19 HDR Plasmid (h) - sc-413741-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE19 Double Nickase Plasmid (h) - sc-413741-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE19 Double Nickase Plasmid (h2) - sc-413741-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE19 CRISPR Activation Plasmid (h) - sc-413741-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE19 CRISPR Activation Plasmid (h2) - sc-413741-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE19 Lentiviral Activation Particles (h) - sc-413741-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE19 Lentiviral Activation Particles (h2) - sc-413741-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE19 siRNA (h) - sc-90097 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZFYVE19 shRNA Plasmid (h) - sc-90097-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZFYVE19 shRNA (h) Lentiviral Particles - sc-90097-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU134821 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23204 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23204 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ZFYVE19 siRNA (Human) - CRJ3707 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZFYVE19 RNAi - H00084936-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ZFYVE19 - MBS8220004 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZFYVE19 (NM_001077268.1) - SHH452468 from Creative biogene

Category siRNA
Species Reactivities Human

Human ZFYVE19 siRNA - orb274208 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZFYVE19 shRNA Plasmid (Human) - CHJ3707 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZFYVE19 miRNA 3'UTR clone - MiUTR1H-11444 from Creative biogene

Species Reactivities Human

ZFYVE19 miRNA 3'UTR clone - MiUTR4H-TG10071 from Creative biogene

Species Reactivities Human
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