MX2

Gene Symbol MX2
Entrez Gene 4600
Alt Symbol MXB
Species Human
Gene Type protein-coding
Description MX dynamin-like GTPase 2
Other Description interferon-induced GTP-binding protein Mx2|interferon-regulated resistance GTP-binding protein MXB|myxovirus (influenza virus) resistance 2|myxovirus resistance protein 2|p78-related protein|second interferon-induced protein p78
Swissprots B7Z5D3 D3DSI7 P20592
Accessions AAC08448 AAC08451 CAB90555 EAX09605 EAX09606 EAX09607 P20592 AK122952 AK124336 AK127895 AK298780 BAH12869 AK308060 AY312582 BC035293 AAH35293 DQ892116 ABM83042 DQ895311 ABM86237 M30818 AAA36338 M33883 AAA36459 XM_005260983 XP_005261040 XM_005260984 XP_005261041 XM_011529571 XP_011527873 XM_011529572 XP_011527874 XM_011529573 XP_011527875 XM_011529574 XP_011527876 NM_002463 NP_002454
Function Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression. {ECO:0000269|PubMed:15184662, ECO:0000269|PubMed:24048477, ECO:0000269|PubMed:24055605, ECO:0000269|PubMed:24121441}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15184662}. Nucleus {ECO:0000269|PubMed:15184662}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:15184662}. Note=Localization to nuclear pores requires GTP-binding.

Mx2 (H-58) - sc-98977 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Mx2 (H-7) - sc-271527 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Mx2 (H-7): sc-271527. Western blot analysis of Mx2 expression in non-transfected: sc-117752 (A) and human Mx2 transfected: sc-114275 (B) 293T whole cell lysates.

Mx2 (K-20) - sc-47195 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Mx2 (N-17) - sc-47197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Mx2 (N-17): sc-47197. Western blot analysis of Mx2 expression in non-transfected: sc-117752 (A) and human Mx2 transfected: sc-114275 (B) 293T whole cell lysates.

Mx2 (N-12) - sc-47196 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Mx2 (N-12): sc-47196. Western blot analysis of Mx2 expression in Jurkat (A) and K-562 (B) whole cell lysates.

Anti-MX2 antibody - ab67388 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-MX2 antibody (ab67388) at 1/500 dilutionLane 1 : MX2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-MX2 antibody - ab196833 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MX2 antibody (ab196833) at 1/500 dilutionLane 1 : 293 cell extractLane 2 : 293 cell extract with synthesized peptide

Anti-MX2 Antibody (N-Terminus) - LS-C345955 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of MX2 Antibody with 721_B Whole Cell lysate.

Anti-MX2 Antibody (aa551-715) - LS-C311542 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MX2 Antibody (aa414-459) - LS-C313832 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

MX2 Antibody - NBP1-81018 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MX2 Antibody [NBP1-81018] - Analysis in control (vector only transfected HEK293T lysate) and mX2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

MX2 Antibody - H00004600-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: MX2 Antibody [H00004600-B01P] - Analysis of MX2 expression in transfected 293T cell line by MX2 polyclonal antibody. Lane 1: MX2 transfected lysate(79.75 KDa). Lane 2: Non-transfected lysate.

Anti-MX2 antibody produced in rabbit - HPA030235 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MX2: <B>Cat. No. HPA030235</B>: Immunohistochemical staining of human skin shows strong cytoplasmic positivity in epidermal cells.

Anti-MX2 antibody produced in mouse - SAB1400172 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Polyclonal Anti-MX2, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400172</B>: Antibody concentration: 1.0 μg/mL using HeLa cells.

MX2 Antibody - N-terminal region (ARP72584_P050) - ARP72584_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MX2-Antibody - AP50672 from Abgent, a WuXi AppTec company

Prices $295.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from U266 cell line,using MX2 Antibody(AP50672). AP50672 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.

MX2 antibody [C2C3], C-term - GTX102775 from GeneTex

Prices $149.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal

MX2 Antibody (OAAB18467) - OAAB18467 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

MX2 Antibody (OAAF04574) - OAAF04574 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

IFI78 antibody - orb157631 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

MX2 Antibody - abx015097 from Abbexa

Host Rabbit
Clonality Polyclonal

MX2 Antibody - abx008961 from Abbexa

Host Rabbit
Clonality Polyclonal

MX2 antibody - H00004600-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Immunofluorescence of purified MaxPab antibody to MX2 on HeLa cell. [antibody concentration 10 ug/ml]

Anti-MxB antibody - STJ94290 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

MX2 antibody - 13278-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal
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