MX2

Gene Symbol MX2
Entrez Gene 4600
Alt Symbol MXB
Species Human
Gene Type protein-coding
Description MX dynamin-like GTPase 2
Other Description interferon-induced GTP-binding protein Mx2|interferon-regulated resistance GTP-binding protein MXB|myxovirus (influenza virus) resistance 2|myxovirus resistance protein 2|p78-related protein|second interferon-induced protein p78
Swissprots B7Z5D3 D3DSI7 P20592
Accessions AAC08448 AAC08451 CAB90555 EAX09605 EAX09606 EAX09607 P20592 AK122952 AK124336 AK127895 AK298780 BAH12869 AK308060 AY312582 BC035293 AAH35293 DQ892116 ABM83042 DQ895311 ABM86237 M30818 AAA36338 M33883 AAA36459 XM_005260983 XP_005261040 XM_005260984 XP_005261041 XM_011529571 XP_011527873 XM_011529572 XP_011527874 XM_011529573 XP_011527875 XM_011529574 XP_011527876 NM_002463 NP_002454
Function Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression. {ECO:0000269|PubMed:15184662, ECO:0000269|PubMed:24048477, ECO:0000269|PubMed:24055605, ECO:0000269|PubMed:24121441}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15184662}. Nucleus {ECO:0000269|PubMed:15184662}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:15184662}. Note=Localization to nuclear pores requires GTP-binding.

Mx2 CRISPR/Cas9 KO Plasmid (h) - sc-400697 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mx2 HDR Plasmid (h) - sc-400697-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mx2 Double Nickase Plasmid (h) - sc-400697-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mx2 Double Nickase Plasmid (h2) - sc-400697-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mx2 CRISPR Activation Plasmid (h) - sc-400697-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mx2 CRISPR Activation Plasmid (h2) - sc-400697-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mx2 Lentiviral Activation Particles (h) - sc-400697-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mx2 Lentiviral Activation Particles (h2) - sc-400697-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mx2 siRNA (h) - sc-61110 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Mx2 shRNA Plasmid (h) - sc-61110-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Mx2 shRNA (h) Lentiviral Particles - sc-61110-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MX2 RNAi - H00004600-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU137811 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14780 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14780 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05733 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05733

MX2 siRNA (Human) - CRH3031 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MX2 (NM_002463.1) - SHH347292 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MX2(NM_002463.1) - SHH209639 from Creative biogene

Category siRNA
Species Reactivities Human

Human MX2 siRNA - orb263533 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MX2 shRNA Plasmid (Human) - CHH3031 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MX2 miRNA 3'UTR clone - MiUTR1H-06541 from Creative biogene

Species Reactivities Human
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