MX2

Gene Symbol MX2
Entrez Gene 4600
Alt Symbol MXB
Species Human
Gene Type protein-coding
Description MX dynamin-like GTPase 2
Other Description interferon-induced GTP-binding protein Mx2|interferon-regulated resistance GTP-binding protein MXB|myxovirus (influenza virus) resistance 2|myxovirus resistance protein 2|p78-related protein|second interferon-induced protein p78
Swissprots B7Z5D3 D3DSI7 P20592
Accessions AAC08448 AAC08451 CAB90555 EAX09605 EAX09606 EAX09607 P20592 AK122952 AK124336 AK127895 AK298780 BAH12869 AK308060 AY312582 BC035293 AAH35293 DQ892116 ABM83042 DQ895311 ABM86237 M30818 AAA36338 M33883 AAA36459 XM_005260983 XP_005261040 XM_005260984 XP_005261041 XM_011529571 XP_011527873 XM_011529572 XP_011527874 XM_011529573 XP_011527875 XM_011529574 XP_011527876 NM_002463 NP_002454
Function Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression. {ECO:0000269|PubMed:15184662, ECO:0000269|PubMed:24048477, ECO:0000269|PubMed:24055605, ECO:0000269|PubMed:24121441}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15184662}. Nucleus {ECO:0000269|PubMed:15184662}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:15184662}. Note=Localization to nuclear pores requires GTP-binding.

MX2 293T Cell Transient Overexpression Lysate(Denatured) - H00004600-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

MX2 overexpression lysate - LY419297 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

MX2 293 Cell Lysate - 409043 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg
Species Mouse

MX2 Overexpression Lysate (Denatured) - H00004600-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
MX2 transfected lysate.

Panoply™ Human MX2 Knockdown Stable Cell Line - CSC-DC009954 from Creative biogene

Category Cell Line
Species Human
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