AIMP1

Gene Symbol	AIMP1
Entrez Gene	9255
Alt Symbol	EMAP2, EMAPII, HLD3, SCYE1, p43
Species	Human
Gene Type	protein-coding
Description	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
Other Description	ARS-interacting multifunctional protein 1|aminoacyl tRNA synthase complex-interacting multifunctional protein 1|endothelial monocyte-activating polypeptide 2|endothelial-monocyte activating polypeptide II|multisynthase complex auxiliary component p43|multisynthetase complex auxiliary component p43|small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
Swissprots	Q6FG28 B4E1S7 Q12904 Q96CQ9 B3KTR2
Accessions	EAX06203 EAX06204 Q12904 AK095951 BAG53174 AK297950 BAG60265 AK303965 BAG64889 AY527272 BC014051 AAH14051 BG941396 BI258927 BM314663 BQ447202 CR542281 CAG47076 DA211424 DC358150 DQ893299 ABM84225 DQ896737 ABM87736 U10117 AAA62202 NM_001142415 NP_001135887 NM_001142416 NP_001135888 NM_004757 NP_004748
Function	Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1- mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7. {ECO:0000269|PubMed:10358004, ECO:0000269|PubMed:11157763, ECO:0000269|PubMed:11306575, ECO:0000269|PubMed:11818442, ECO:0000269|PubMed:1223731
Subcellular Location	Nucleus. Cytoplasm, cytosol. Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Secreted {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels (By similarity). Also secreted in response to hypoxia and both apoptotic and necrotic cell death. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AIMP1 / EMAP II ELISA Kit (Sandwich ELISA) - LS-F7291 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 125 pg/ml Range 125-8000 pg/ml

Mouse AIMP1 / EMAP II ELISA Kit (Sandwich ELISA) - LS-F7292 from LifeSpan Bioscience Category ELISA Kit Prices $810.00 Sizes 1 plate Sensitivity 31.2 pg/ml Range 125-8000 pg/ml

Mouse AIMP1 / EMAP II ELISA Kit (Sandwich ELISA) - LS-F10776 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 125-8000 pg/ml

Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1, AIMP1, Human, ELISA Kit - E-EL-H0204 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 75 Range 125-8000pg/mL

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), Human, ELISA Kit - CSB-EL020871HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), Human, ELISA Kit - E01A1968 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, AIMP1, Human, ELISA Kit - E2214h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1), Human, ELISA Kit - SEL761Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 43pg/mL Range 125-8,000pg/mL

Echinoderm Microtubule Associated Protein Like Protein 2 (EML2), Human, ELISA Kit - SEQ641Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 0.113ng/mL Range 0.312-20ng/mL

Human AIMP1(Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1) ELISA Kit - E-EL-H0204 from Elabscience Category ELISA Kit Sensitivity 75.00 pg/mL Range 125.00—8000 pg/mL

Human AIMP1 (Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1) CLIA Kit - E-CL-H0186 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

AIMP1, ELISA Kit - MBS2503380 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 75pg/mL Range 125--8000pg/mL

Aminoacyl tRNA synthase complex interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7226135 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7225877 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7226452 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7228020 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7219837 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7235709 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7233438 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7207844 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7239084 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7250624 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7244024 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), ELISA Kit - MBS7235833 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1), ELISA Kit - MBS2019478 from MyBioSource Category ELISA Kit Prices $420.00, $625.00, $855.00, $3,510.00, $6,365.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 12.4pg/mL. Range 31.25-2000pg/mL

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