EXO5

Gene Symbol	EXO5
Entrez Gene	64789
Alt Symbol	C1orf176, DEM1, Exo V, hExo5
Species	Human
Gene Type	protein-coding
Description	exonuclease 5
Other Description	defects in morphology 1 homolog|defects in morphology protein 1 homolog|exonuclease V|probable exonuclease V
Swissprots	Q5SWN1 Q5SWM9 Q5SWM8 D3DPV4 Q9H790 Q8WTW9 Q5SWM7 Q5SWN0
Accessions	EAX07210 EAX07211 EAX07212 EAX07213 EAX07214 Q9H790 AF086542 AK021507 AK023245 AK024797 BAB15008 AK094092 BC021969 AAH21969 HQ448143 ADQ32624 XM_005271125 XP_005271182 XM_005271126 XP_005271183 XM_005271128 XP_005271185 XM_011541970 XP_011540272 NM_022774 NP_073611
Function	Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends. Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting; however the sliding and the 3'-5' exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5'-directionality activity. {ECO:0000269|PubMed:23095756}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:23095756}. Cytoplasm, cytosol {ECO:0000269|PubMed:23095756}. Note=Localizes to repair foci in response to DNA damage.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EXO5 / Exonuclease 5 Antibody Blocking Peptide - LS-E243 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EXO5 / Exonuclease 5 Antibody Blocking Peptide - LS-E24228 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DEM1-Antibody-Center-Blocking-Peptide - BP10478c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human EXO5 protein - orb244948 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Recombinant Human EXO5 - EXO5-1419H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Probable exonuclease V(DEM1) - CSB-YP863995HU CSB-BP863995HU CSB-MP863995HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Exonuclease V - CSB-EP863995HU from Cusabio Category Protein Source E.coli Species Human

EXO5 Protein - abx163337 from Abbexa Category Protein Species Human, Mouse

Exonuclease V - TP303370 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Exonuclease V, Recombinant Protein - MBS1379987 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,140.00, $1,180.00, $1,370.00, $1,370.00, $1,815.00, $2,280.00, $2,280.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 50 µg (Baculovirus), 1 mg (E-Coli), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

DEM1 Protein - NBP1-88493PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

EXO5 Peptide, Human - M34GP05126H from Creative Peptides Category Peptide Source Synthetic. Species Human

EXO5 Recombinant Protein (OPCA02466) - OPCA02466 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant human Exonuclease V - AP71525 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Exonuclease V, Recombinant Protein - MBS9421387 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Recombinant Human Exonuclease V (EXO5) - RPC23557 from Biomatik Category Protein Prices $187.00, $342.00, $1,692.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Human

Recombinant Human EXO5 Protein (1-373 aa), His-SUMO-tagged - EXO5-1119H from Creative Biomart Category Protein Source E. coli Species Human

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