MMP14

Gene Symbol	MMP14
Entrez Gene	4323
Alt Symbol	MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS
Species	Human
Gene Type	protein-coding
Description	matrix metallopeptidase 14 (membrane-inserted)
Other Description	matrix metalloproteinase-14|membrane type 1 metalloprotease|membrane-type-1 matrix metalloproteinase
Swissprots	Q92678 Q6GSF3 A8K5L0 P50281
Accessions	AAF24178 AAV40837 BAC53889 EAW66236 EAW66237 P50281 AK291325 BAF84014 AK312657 BAG35540 BC039581 BC064803 AAH64803 BQ009340 D26512 BAA05519 HE978355 CCK73138 HY075830 U41078 AAA83770 X83535 CAA58519 X90925 CAA62432 Z48481 CAA88372 NM_004995 NP_004986
Function	Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro- MMP2. {ECO:0000269|PubMed:12714657, ECO:0000269|PubMed:20837484, ECO:0000269|PubMed:22065321}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Melanosome. Cytoplasm. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm.
Tissue Specificity	Expressed in stromal cells of colon, breast, and head and neck. Expressed in lung tumors. {ECO:0000269|PubMed:18223680}.
Top Pathways	GnRH signaling pathway, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MMP14 Human SimpleStep ELISA™ Kit - ab197747 from Abcam Category ELISA Kit Prices $470.00 Sizes 1 x 96 tests Sensitivity 0.137 ng/ml Range 25 ng/ml - 0.391 ng/ml

Human MMP14 ELISA Kit (Sandwich ELISA) - LS-F5858 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.57 ng/ml Range 1.56-100 ng/ml

Mouse/Human/Rat MMP14 ELISA Kit (Cell-Based ELISA) - LS-F2157 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 1.56-100 ng/ml

Mouse MMP14 ELISA Kit (Sandwich ELISA) - LS-F7353 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 1.56-100 ng/ml

Human Total MMP-14/MT1-MMP DuoSet ELISA - DY918-05 from R&D Systems Category ELISA Kit Prices $299.00 Sizes 1 kit (for 5 Plates) Range 0.63 - 20 ng/mL

Human MMP14 ELISA Kit - abx152352 from Abbexa Category ELISA Kit Sensitivity 0.58 ng/ml Range 1.563 ng/ml - 100 ng/ml

Matrix Metalloproteinase 14 (MMP14), Human, ELISA Kit - SEC056Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.63ng/mL Range 1.56-100ng/mL

Matrix Metalloproteinase 14, MMP-14, Human, ELISA Kit - CSB-E13157h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.8 ng/ml Range 3.12 ng/ml-200 ng/ml

Matrix metalloproteinase-14, MMP14, Human, ELISA Kit - E2056h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 31.2-2000 pg/mL

MMP-14 Colorimetric Cell-Based ELISA Kit - CB5458 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

MMP-14 Hemopexin Antibody - GWB-C0CAEC from Genway Biotech Category ELISA Kit Prices $468.00 Sizes 100 µg

MMP-14/MT1-MMP, Antibody - GWB-CFFD51 from Genway Biotech Category ELISA Kit Prices $451.00 Sizes 1 ml

Human MMP-14(Matrix Metalloproteinase 14) ELISA Kit - E-EL-H2454 from Elabscience Category ELISA Kit Sensitivity 0.38 ng/mL Range 0.63—40 ng/mL

matrix metallopeptidase 14 (membrane-inserted) , ELISA Kit - MBS704825 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human MMP-14 is typically less than 0.78 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 3.12 ng/ml-200 ng/ml.

Matrix metalloproteinase 14, ELISA Kit - MBS7245318 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Matrix metalloproteinase 14, ELISA Kit - MBS7202358 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Matrix metalloproteinase 14, ELISA Kit - MBS7244897 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Matrix metalloproteinase 14, ELISA Kit - MBS7213744 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Matrix metalloproteinase 14, ELISA Kit - MBS7243704 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Matrix metalloproteinase 14, ELISA Kit - MBS7223249 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Matrix metalloproteinase 14, ELISA Kit - MBS7222490 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Matrix metalloproteinase 14, ELISA Kit - MBS7201754 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Matrix metalloproteinase 14, ELISA Kit - MBS7233761 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Matrix metalloproteinase 14, ELISA Kit - MBS7249910 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Matrix Metalloproteinase 14 (MMP14), ELISA Kit - MBS2021894 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 37.25pg/mL. Range 93.75-6000pg/mL

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