SUZ12

Gene Symbol SUZ12
Entrez Gene 23512
Alt Symbol CHET9, JJAZ1
Species Human
Gene Type protein-coding
Description SUZ12 polycomb repressive complex 2 subunit
Other Description chET 9 protein|chromatin precipitated E2F target 9 protein|joined to JAZF1 protein|polycomb protein SUZ12|suppressor of zeste 12 homolog|suppressor of zeste 12 protein homolog
Swissprots Q96BD9 Q15022
Accessions EAW80258 Q15022 AK074333 AK290014 BAF82703 BC015704 AAH15704 BC018583 D63881 BAA09931 DB501687 ES313164 XM_005257954 XP_005258011 XM_006721794 XP_006721857 XM_011524576 XP_011522878 XM_011524577 XP_011522879 XM_011524578 XP_011522880 NM_015355 NP_056170
Function Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. {ECO:0000269|PubMed:15225548, ECO:0000269|PubMed:15231737, ECO:0000269|PubMed:15385962, ECO:0000269|PubMed:16618801, ECO:0000269|PubMed:17344414, ECO:0000269|PubMed:18285464}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15231737}.
Tissue Specificity Overexpressed in breast and colon cancer. {ECO:0000269|PubMed:15231737, ECO:0000269|PubMed:15684044}.

SUZ12 293 Cell Lysate - 407002 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg
Species Drosophila

SUZ12 Overexpression Lysate (Native) - NBL1-16629 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: SUZ12 Overexpression Lysate (Adult Normal) [NBL1-16629] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SUZ12.

SUZ12 (h): 293 Lysate - sc-111839 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

SUZ12 Over-expression Lysate Product - GWB-31C0D4 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

SUZ12-knockout Cell lysate - LC810337 from Acris Antibodies

Category Cell Lysate
Prices $495.00
Sizes 100 µg

Panoply™ Human SUZ12 Knockdown Stable Cell Line - CSC-DC015432 from Creative biogene

Category Cell Line
Species Human

Human SUZ12 Knockout Cell Line-HeLa - CSC-RT0598 from Creative biogene

Category Cell Line
Species Human

SUZ12 KO Cell Lysate-HeLa - CLKO-0103 from Creative biogene

Category Cell Lysate
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