SUZ12

Gene Symbol SUZ12
Entrez Gene 23512
Alt Symbol CHET9, JJAZ1
Species Human
Gene Type protein-coding
Description SUZ12 polycomb repressive complex 2 subunit
Other Description chET 9 protein|chromatin precipitated E2F target 9 protein|joined to JAZF1 protein|polycomb protein SUZ12|suppressor of zeste 12 homolog|suppressor of zeste 12 protein homolog
Swissprots Q96BD9 Q15022
Accessions EAW80258 Q15022 AK074333 AK290014 BAF82703 BC015704 AAH15704 BC018583 D63881 BAA09931 DB501687 ES313164 XM_005257954 XP_005258011 XM_006721794 XP_006721857 XM_011524576 XP_011522878 XM_011524577 XP_011522879 XM_011524578 XP_011522880 NM_015355 NP_056170
Function Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. {ECO:0000269|PubMed:15225548, ECO:0000269|PubMed:15231737, ECO:0000269|PubMed:15385962, ECO:0000269|PubMed:16618801, ECO:0000269|PubMed:17344414, ECO:0000269|PubMed:18285464}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15231737}.
Tissue Specificity Overexpressed in breast and colon cancer. {ECO:0000269|PubMed:15231737, ECO:0000269|PubMed:15684044}.

Human SUZ12 full length protein - ab196414 from Abcam

Category Protein
Source Baculovirus infected sf9 cells
Species Human
4-20% SDS-PAGE analysis of 2 μg ab196414 with Coomassie staining.

Human SUZ12 peptide - ab12389 from Abcam

Category Peptide

Human SUZ12 protein fragment - ab112401 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab112401. Stained with Coomassie Blue

SUZ12 Antibody Blocking Peptide - LS-E14135 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SUZ12 Antibody Blocking Peptide - LS-E11401 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human SUZ12 Protein - H00023512-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

SUZ12 Protein Lysate (APL10305) - APL10305 from Aviva Systems Biology

Category Protein
Prices $219.00
Sizes 200 µg

SUZ12 Protein Lysate (APL10465) - APL10465 from Aviva Systems Biology

Category Protein
Prices $219.00
Sizes 200 µg

SUZ12 Protein Lysate (APL10466) - APL10466 from Aviva Systems Biology

Category Protein
Prices $219.00
Sizes 200 µg

SUZ12 Blocking Peptide - 33R-9083 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SUZ12 Blocking Peptide - 33R-2719 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SUZ12 - H00023512-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

SUZ12 - H00023512-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

SUZ12 Peptide - 7701P from ProSci

Category Peptide
Species Human

Recombinant Human SUZ12 - SUZ12-31487TH from Creative Biomart

Category Protein
Source Wheat germ

Recombinant Suppressor Of Zeste 12 Homolog (SUZ12) - RPM329Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Suppressor Of Zeste 12 Homolog (SUZ12) - RPM329Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Polycomb protein SUZ12(SUZ12) - CSB-YP621859HU CSB-EP621859HU CSB-BP621859HU CSB-MP621859HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

SUZ12 Protein - abx164076 from Abbexa

Category Protein
Species Human, Mouse

SUZ12 - TP302362 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
SUZ12

Polycomb protein SUZ12 (SUZ12), Recombinant Protein - MBS1437089 from MyBioSource

Category Protein
Prices $1,550.00, $1,550.00, $1,780.00, $1,780.00, $2,670.00, $2,670.00, $3,110.00, $3,110.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

SUZ12 Recombinant Protein Antigen - NBP2-33834PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

SUZ12 Antibody - SH-A16100 from Novatein Biosciences

Prices $315.00
Sizes 100 µl
Species Human, Mouse, Rat

Suz12 antibody ( mAb ) , 100 ug - HM-AB2036 from Novatein Biosciences

Prices $442.00
Sizes 100 µg

Suz12 antibody ( mAb ) , 10 ug - HM-AB2037 from Novatein Biosciences

Prices $91.00
Sizes 10 µg
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