Gene Symbol | HS2ST1 |
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Entrez Gene | 9653 |
Alt Symbol | dJ604K5.2 |
Species | Human |
Gene Type | protein-coding |
Description | heparan sulfate 2-O-sulfotransferase 1 |
Other Description | 2-O-sulfotransferase|2OST |
Swissprots | Q9H441 Q9NUJ9 O75036 Q8TAC5 Q32NB5 Q7LGA3 D3DT22 |
Accessions | EAW73170 EAW73171 EAW73172 EAW73173 Q7LGA3 AB007917 BAA32293 AB024568 BAA89250 AF086247 AK023260 BAG51177 BC025384 AAH25384 BC025990 AAH25990 BC108735 AAI08736 BF431947 JF432623 ADZ15840 NM_001134492 NP_001127964 NM_012262 NP_036394 |
Function | Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high- affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
Human HS2ST1 protein fragment - ab127066 from Abcam
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HS2ST1 Antibody Blocking Peptide - LS-E17623 from LifeSpan Bioscience
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HS2ST1 Antibody Blocking Peptide - LS-E17624 from LifeSpan Bioscience
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HS2ST1 Antibody Blocking Peptide - LS-E9148 from LifeSpan Bioscience
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Recombinant Human Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Protein - H00009653-Q01 from Novus Biologicals
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Recombinant Human Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Protein - H00009653-P01 from Novus Biologicals
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Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Peptide - P2677 from Novus Biologicals
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HS2ST1-Antibody-N-term-Blocking-Peptide - BP7648a from Abgent, a WuXi AppTec company
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Recombinant Human HS2ST1, CF - 6335-ST-020 from R&D Systems
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HS2ST1 Blocking Peptide - 33R-3410 from Fitzgerald
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HS2ST1 Blocking Peptide - 33R-3656 from Fitzgerald
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HS2ST1 / 2OST - H00009653-P01 from Acris Antibodies
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HS2ST1 / 2OST - H00009653-Q01-10 from Acris Antibodies
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HS2ST1 / 2OST - H00009653-Q01-25 from Acris Antibodies
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HS2ST1 fusion protein - ag3111 from Proteintech Group
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Recombinant Human HS2ST1, His-tagged - HS2ST1-105H from Creative Biomart
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Recombinant Heparan Sulfate-2-O-Sulfotransferase 1 (HS2ST1) - RPH881Hu01 from Uscn Life Science Inc.
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Recombinant Human Heparan sulfate 2-O-sulfotransferase 1(HS2ST1) - CSB-YP010746HU CSB-EP010746HU CSB-BP010746HU CSB-MP010746HU from Cusabio
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Recombinant Human HS2ST1 Protein, CF - 6335-ST from R&D Systems
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Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Protein - NBP1-91983PEP from Novus Biologicals
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Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Recombinant Protein Antigen - NBP1-91982PEP from Novus Biologicals
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HS2ST1-Blocking-Peptide-Center - BP7648c from Abgent, a WuXi AppTec company
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HS2ST1 Peptide, Human - M34GP07257H from Creative Peptides
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HS2ST1 Recombinant Protein (OPCD03984) - OPCD03984 from Aviva Systems Biology
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Heparan Sulfate 2-O-sulfotransferase 1 Human,, Recombinant Protein - MBS636651 from MyBioSource
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