Gene Symbol | HS2ST1 |
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Entrez Gene | 9653 |
Alt Symbol | dJ604K5.2 |
Species | Human |
Gene Type | protein-coding |
Description | heparan sulfate 2-O-sulfotransferase 1 |
Other Description | 2-O-sulfotransferase|2OST |
Swissprots | Q9H441 Q9NUJ9 O75036 Q8TAC5 Q32NB5 Q7LGA3 D3DT22 |
Accessions | EAW73170 EAW73171 EAW73172 EAW73173 Q7LGA3 AB007917 BAA32293 AB024568 BAA89250 AF086247 AK023260 BAG51177 BC025384 AAH25384 BC025990 AAH25990 BC108735 AAI08736 BF431947 JF432623 ADZ15840 NM_001134492 NP_001127964 NM_012262 NP_036394 |
Function | Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high- affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
HS2ST1 (G-10) - sc-376530 from Santa Cruz Biotechnology
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HS2ST1 (H-170) - sc-292203 from Santa Cruz Biotechnology
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HS2ST1 (E-18) - sc-103549 from Santa Cruz Biotechnology
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HS2ST1 (T-13) - sc-103551 from Santa Cruz Biotechnology
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HS2ST1 (Z-23) - sc-130779 from Santa Cruz Biotechnology
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Anti-HS2ST1 antibody - ab108541 from Abcam
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Anti-HS2ST1 antibody - ab63166 from Abcam
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Anti-HS2ST1 antibody - ab89052 from Abcam
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Anti-HS2ST1 Antibody - LS-C178443 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody (N-Terminus, AP) - LS-C244635 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody (N-Terminus, APC) - LS-C244637 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody (N-Terminus, Biotin) - LS-C244638 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody (N-Terminus, FITC) - LS-C244639 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody (N-Terminus, PE) - LS-C244640 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody (N-Terminus, Azide-free, HRP) - LS-C247626 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody - LS-C308304 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody - LS-C310664 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody (N-Terminus) - LS-C111188 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody (aa252-301) - LS-C111189 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody (N-Terminus) - LS-C327536 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody - LS-C178485 from LifeSpan Bioscience
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Anti-HS2ST1 Antibody (aa16-45) - LS-C97542 from LifeSpan Bioscience
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Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody (738306) - MAB6335 from Novus Biologicals
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Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody - NBP1-91982 from Novus Biologicals
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Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody - NBP1-79294 from Novus Biologicals
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