P4HTM

Gene Symbol	P4HTM
Entrez Gene	54681
Alt Symbol	EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4
Species	Human
Gene Type	protein-coding
Description	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
Other Description	HIF-PH4|HIF-prolyl hydroxylase 4|HPH-4|P4H with transmembrane domain|Prolyl hydroxlase domain-containing 4|hypoxia inducible factor prolyl 4 hydroxylase|hypoxia-inducible factor prolyl 4-hydroxylase|hypoxia-inducible factor prolyl hydroxylase 4|proline 4-hydroxylase|transmembrane prolyl 4-hydroxylase
Swissprots	Q8WV55 Q9NXG6 Q96F22 Q9BW77 Q8TCJ9 Q6PAG6
Accessions	EAW64934 EAW64935 EAW64936 EAW64937 EAW64938 EAW64939 EAW64940 Q9NXG6 AI079878 AK000269 BAA91045 AK309082 AL713728 CAD28518 AW072069 AY198406 AAO43431 BC000580 AAH00580 BC011710 AAH11710 BC018731 BC047566 AAH47566 BC060321 AAH60321 XM_011533845 XP_011532147 XM_011533846 XP_011532148 XR_940459 NM_177938 NP_808807 NM_177939 NP_808808 NM_017732
Function	Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. {ECO:0000269|PubMed:17726031}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:12163023, ECO:0000269|PubMed:17726031}; Single-pass type II membrane protein {ECO:0000269|PubMed:12163023, ECO:0000269|PubMed:17726031}.
Tissue Specificity	Widely expressed with highest levels in adult pancreas, heart, skeletal muscle, brain, placenta, kidney and adrenal gland. Expressed at lower levels in epiphyseal cartilage and in fibroblasts. {ECO:0000269|PubMed:12163023, ECO:0000269|PubMed:17726031}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PHD4/prolyl hydroxylase full length protein - ab162816 from Abcam Category Protein Source Wheat germ Species Human

PH4 / P4HTM Antibody Blocking Peptide - LS-E21101 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PH4 / P4HTM Antibody Blocking Peptide - LS-E21102 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PHD4/HIF Prolyl Hydroxylase 4 Recombinant Protein - H00054681-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Human P4HTM protein - orb246282 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

PH4 Blocking Peptide - 33R-3321 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PH4 Blocking Peptide - 33R-8025 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P4HTM / PH4 - H00054681-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

P4HTM / PH4 - H00054681-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

P4HTM fusion protein - ag9123 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

P4HTM fusion protein - Ag9259 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human P4HTM, GST-tagged - P4HTM-1500H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Transmembrane prolyl 4-hydroxylase(P4HTM) - CSB-YP878913HU CSB-BP878913HU CSB-MP878913HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Transmembrane prolyl 4-hydroxylase - CSB-EP878913HU from Cusabio Category Protein Source E.coli Species Human

PHD4/HIF Prolyl Hydroxylase 4 Recombinant Protein Antigen - NBP1-83989PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

P4HTM Peptide, Human - M34GP11218H from Creative Peptides Category Peptide Source Synthetic. Species Human

P4HTM Recombinant Protein (OPCA02507) - OPCA02507 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant human Transmembrane prolyl 4-hydroxylase - AP71573 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Recombinant Human Transmembrane prolyl 4-hydroxylase (P4HTM) - RPC23655 from Biomatik Category Protein Prices $187.00, $342.00, $1,692.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Human

Search more