PRG2

Gene Symbol	PRG2
Entrez Gene	5553
Alt Symbol	BMPG, MBP, MBP1
Species	Human
Gene Type	protein-coding
Description	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
Other Description	bone marrow proteoglycan|bone-marrow proteoglycan|eosinophil granule major basic protein|eosinophil major basic protein|natural killer cell activator|proteoglycan 2 preproprotein
Swissprots	Q6ICT2 P13727 P81448 A6XMW0 Q14227 B2R5I1
Accessions	AAA35796 CBH19418 P13727 AK312195 BAG35128 AU135652 BC005929 AAH05929 BQ445845 BX395670 BX397850 BX454677 CB997424 CR450311 CAG29307 DA841825 DQ846874 ABI63361 DQ893180 ABM84106 DQ896482 ABM87481 M35670 AAA35965 M36805 AAA36203 X14088 CAA32250 X65787 CAA46670 Y00809 CAA68751 Z26248 CAA81207 NM_001243245 NP_001230174 NM_001302926 NP_001289855 NM_001302927 NP_001289856 NM_002728 NP_002719
Function	Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. {ECO:0000269|PubMed:10913121}.
Subcellular Location	Bone marrow proteoglycan: Secreted. Note=The proform is secreted.
Tissue Specificity	High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon. {ECO:0000269|PubMed:10491647, ECO:0000269|PubMed:7526035}.
Top Pathways	Asthma

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse PRG2 / Proteoglycan 2 ELISA Kit (Sandwich ELISA) - LS-F6822 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.312 ng/ml Range 3.13-200 ng/ml

Human PRG2 / Proteoglycan 2 ELISA Kit (Sandwich ELISA) - LS-F5876 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 3.13 ng/ml Range 3.13-200 ng/ml

Eosinophil granule major basic protein (EMBP/MBP), Human, ELISA Kit - CSB-E17578h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7247064 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bone marrow proteoglycan (PRG2/MBP) - MBS9310726 from MyBioSource Category ELISA Kit

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7208740 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7238703 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7214401 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7236689 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/mL.

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7201392 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7236471 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7249558 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7243436 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7244974 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7201200 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bone marrow proteoglycan (PRG2), ELISA Kit - MBS7250886 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Major Basic Protein (MBP), ELISA Kit - MBS2022666 from MyBioSource Category ELISA Kit Prices $370.00, $550.00, $750.00, $3,065.00, $5,550.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.249ng/mL. Range 0.625-40ng/mL.

Major Basic Protein (MBP), ELISA Kit - MBS9308460 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Major Basic Protein (MBP), ELISA Kit - MBS2019468 from MyBioSource Category ELISA Kit Prices $355.00, $540.00, $730.00, $2,985.00, $5,410.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 1.37ng/mL Range 3.12-200ng/mL.

Major Basic Protein (MBP), ELISA Kit - MBS9309876 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml. Range 0.625 ng/ml - 20 ng/ml.

major basic protein, MBP, ELISA Kit - MBS9301828 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) , ELISA Kit - MBS906454 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <1.17 ng/ml Range 4.69 ng/ml-300 ng/ml

ELISA Kit for Major Basic Protein (MBP) - SEB650Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 1.16ng/mL. Range 3.13-200ng/mL The standard curve concentrations used for the ELISA’s were 200ng/mL, 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL

ELISA Kit for Major Basic Protein (MBP) - SEB650Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.238ng/mL. Range 0.625-40ng/mL The standard curve concentrations used for the ELISA’s were 40ng/mL, 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL

CLIA Kit for Major Basic Protein (MBP) - SCB650Mu from Uscn Life Science Inc. Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.03ng/mL. Range 0.055-40ng/mL The standard curve concentrations used for the CLIA’s were 40ng/mL, 13.333ng/mL, 4.444ng/mL, 1.481ng/mL, 0.494ng/mL, 0.165ng/mL, 0.055ng/mL

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