TOP2A

Gene Symbol	TOP2A
Entrez Gene	7153
Alt Symbol	TOP2, TP2A
Species	Human
Gene Type	protein-coding
Description	topoisomerase (DNA) II alpha 170kDa
Other Description	DNA gyrase|DNA topoisomerase (ATP-hydrolyzing)|DNA topoisomerase 2-alpha|DNA topoisomerase II, 170 kD|DNA topoisomerase II, alpha isozyme
Swissprots	Q9HB24 P11388 Q9UQP9 Q9HB25 Q71UQ5 Q71UN1 Q9HB26 B2RTS1 Q9UP44
Accessions	AAC16736 AAC23518 AAC77388 ABA01496 CAA09762 EAW60661 EAW60662 EAW60663 P11388 AF285157 AAG13403 AF285158 AAG13404 AF285159 AAG13405 AK024080 BC013429 BC062677 BC140791 AAI40792 DB069825 J04088 AAA61209 L47276 L47277 XM_005257632 XP_005257689 XM_011525165 XP_011523467 NM_001067 NP_001058
Function	Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity). {ECO:0000250|UniProtKB:Q01320, ECO:0000269|PubMed:18790802, ECO:0000269|PubMed:22013166, ECO:0000269|PubMed:22323612}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:22013166}. Nucleus, nucleoplasm {ECO:0000269|PubMed:22013166}. Note=Generally located in the nucleoplasm.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Topoisomerase II alpha protein fragment - ab159735 from Abcam Category Protein Source Wheat germ Species Human

TOP2A / Topoisomerase II Alpha Antibody Blocking Peptide - LS-E3964 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TOP2A / Topoisomerase II Alpha Antibody Blocking Peptide - LS-E10603 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TOP2A / Topoisomerase II Alpha Antibody Blocking Peptide - LS-E10025 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TOP2A Protein - H00007153-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TOP2A-Antibody-C-term-Blocking-peptide - BP16175b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TOP2A-Antibody-C-term-Blocking-Peptide - BP9248b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TOP2A Blocking Peptide - 33R-9809 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Topoisomerase II Protein - abx069382 from Abbexa Category Protein Source E.coli Species Human

TOP2A - H00007153-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TOP2A - H00007153-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TOP2A fusion protein - Ag19551 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human TOP2A, GST-tagged - TOP2A-2611H from Creative Biomart Category Protein Source Wheat germ

Recombinant Human TOP2A - TOP2A-115H from Creative Biomart Category Protein Species Human

Recombinant Human TOP2A, GST-tagged - TOP2A-3351H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human TOP2A - TOP2A-199H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Topoisomerase II (TOP2) - RPA792Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Topoisomerase II (TOP2) - RPA792Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Topoisomerase II (TOP2) - RPA792Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Topoisomerase II (TOP2) - RPA792Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Topoisomerase 2 alpha Blocking Peptide - CBP2182 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

Topo IIα (E1102) Peptide - BS2643P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Topo IIα (Q14) Peptide - BS3010P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Topoisomerase II (TOP2) - RPA792Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human DNA topoisomerase 2-alpha(TOP2A) ,partial - CSB-YP024060HU CSB-EP024060HU CSB-BP024060HU CSB-MP024060HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Search more