CCL18

Gene Symbol	CCL18
Entrez Gene	6362
Alt Symbol	AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
Other Description	C-C motif chemokine 18|CC chemokine PARC|CC chemokine ligand 18|alternative macrophage activation-associated CC chemokine 1|chemokine (C-C), dendritic|dendritic cell chemokine 1|macrophage inflammatory protein 4|pulmonary and activation-regulated chemokine|small inducible cytokine A18|small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated|small-inducible cytokine A18
Swissprots	Q53X71 P55774 B5BUM2
Accessions	AAC32287 AAD30390 BAA34368 CAJ15096 EAW80102 P55774 AB000221 BAA21670 AB451458 BAG70272 BC069700 AAH69700 BC096124 AAH96124 BC096125 AAH96125 BC096126 AAH96126 BC096127 AAH96127 BU617136 CR407660 CAG28588 HQ448456 ADQ32936 Y13710 CAA74039 NM_002988 NP_002979
Function	Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. {ECO:0000269|PubMed:11745396, ECO:0000269|PubMed:11978786}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid. {ECO:0000269|PubMed:11745396}.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MIP4 (CCL18) Human ELISA Kit - ab100620 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 2 pg/ml Range 2.74 pg/ml - 2000 pg/ml

Human CCL18 / PARC ELISA Kit (Sandwich ELISA) - LS-F2626 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 2.74-2000 pg/ml

Human CCL18 / PARC ELISA Kit (Sandwich ELISA) - LS-F4785 from LifeSpan Bioscience Category ELISA Kit Prices $470.00 Sizes 1 plate Sensitivity 36 pg/ml Range 2.74-2000 pg/ml

Human CCL18 / PARC ELISA Kit (Sandwich ELISA) - LS-F468 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 2 pg/ml Range 2.74-2000 pg/ml

Human CCL18 / PARC ELISA Kit (Sandwich ELISA) - LS-F11051 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 0.156 Range 2.74-2000 pg/ml

Human PARC / CCL18 ELISA Kit - RAB0051 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

CCL18/PARC BioAssay™ ELISA Kit, Human - 143747 from USBiological Life Science Category ELISA Kit Sensitivity < 10pg/ml Range 7.8-500pg/ml

Human CCL18/PARC Quantikine ELISA Kit - DCL180 from R&D Systems Category ELISA Kit Sensitivity 1.77 pg/mL Range 18.8 - 1,200 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, EDTA Plasma, Urine, Tissue Lysates)

Human CCL18/PARC DuoSet ELISA - DY394 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 7.81 - 500 pg/mL

Quantikine Immunoassay Control Set 756 for Human CCL18/PARCFor use with catalog number DCL180 - QC59 from R&D Systems Category ELISA Kit

Quantikine Immunoassay Control Set 868 for Human CCL18/PARC - QC59B from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Human CCL18/PARC Quantikine ELISA Kit - DCL180B from R&D Systems Category ELISA Kit Prices $509.00 Sizes 1 kit Sensitivity 1.77 pg/mL Range 18.8 - 1,200 pg/mL (Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine)

Human AmAC-1 ELISA Kit - abx054933 from Abbexa Category ELISA Kit

Human CCL18 ELISA Kit - abx056037 from Abbexa Category ELISA Kit

Human PARC ELISA Kit - abx152646 from Abbexa Category ELISA Kit Sensitivity 30 pg/ml Range 78.125 pg/ml - 5000 pg/ml

Human PARC ELISA Kit - abx054656 from Abbexa Category ELISA Kit

Alternative macrophage activation-associated CC chemokine 1, Human, ELISA Kit - E01A0790 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 250-5000pg/ml

C-C motif chemokine 18, CCL18, Human, ELISA Kit - E0211h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 0.156-10 ng/mL

CCL18/PARC, Human, ELISA Kit - PB-0686 from ARP American Research Products Category ELISA Kit Prices $418.00 Sizes 96 t Sensitivity < 10 pg/ml Range 7.8pg/ml-500pg/ml

Cullin 9 (CUL9), Human, ELISA Kit - SEF360Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.118ng/mL Range 0.312-20ng/mL

Pulmonary Activation Regulated Chemokine, PARC/CCL18, Human, ELISA Kit - E-EL-H1270 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 46.875 Range 78.125-5000pg/mL

Pulmonary activation regulated chemokine, PARC, Human, ELISA Kit - CSB-E09941h from ARP American Research Products Category ELISA Kit Prices $565.00, $835.00, $837.00, $839.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 2.pg/ml Range 7.8 pg/ml-500 pg/ml

Pulmonary Activation Regulated Chemokine, PARC, Mouse, ELISA Kit - E-EL-M0991 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 46.875 Range 78.125-5000pg/mL

Pulmonary Activation Regulated Chemokine, PARC/CCL18, Rabbit, ELISA Kit - E-EL-RB1240 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Alternative Macrophage Activation-associated CC Chemokine 1, AmAC-1, Chicken, ELISA Kit - E-EL-Ch0006 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

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