CCL18

Gene Symbol	CCL18
Entrez Gene	6362
Alt Symbol	AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
Other Description	C-C motif chemokine 18|CC chemokine PARC|CC chemokine ligand 18|alternative macrophage activation-associated CC chemokine 1|chemokine (C-C), dendritic|dendritic cell chemokine 1|macrophage inflammatory protein 4|pulmonary and activation-regulated chemokine|small inducible cytokine A18|small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated|small-inducible cytokine A18
Swissprots	Q53X71 P55774 B5BUM2
Accessions	AAC32287 AAD30390 BAA34368 CAJ15096 EAW80102 P55774 AB000221 BAA21670 AB451458 BAG70272 BC069700 AAH69700 BC096124 AAH96124 BC096125 AAH96125 BC096126 AAH96126 BC096127 AAH96127 BU617136 CR407660 CAG28588 HQ448456 ADQ32936 Y13710 CAA74039 NM_002988 NP_002979
Function	Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. {ECO:0000269|PubMed:11745396, ECO:0000269|PubMed:11978786}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid. {ECO:0000269|PubMed:11745396}.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Macrophage Inflammatory Protein 4 full length protein - ab192128 from Abcam Category Protein Prices $192.00 Sizes 25 µg Source E. coli Species Human

Active Macrophage Inflammatory Protein 4 full length protein - ab9850 from Abcam Category Protein Prices $110.00, $257.00 Sizes 2 µg, 10 µg Source E. coli

Human Macrophage Inflammatory Protein 4 full length protein - ab173065 from Abcam Category Protein Source E. coli Species Human

Human Macrophage Inflammatory Protein 4 full length protein - ab175168 from Abcam Category Protein Source Synthetic Species Human

Human Macrophage Inflammatory Protein 4 full length protein - ab176061 from Abcam Category Protein Source Synthetic Species Human

Human Macrophage Inflammatory Protein 4 protein fragment - ab101822 from Abcam Category Protein Source E. coli Species Human

CCL18 / PARC Antibody Blocking Peptide - LS-E10748 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CCL18/PARC Protein - NBP2-35041 from Novus Biologicals Category Protein Prices $69.00, $169.00, $2,669.00 Sizes 2 µg, 10 µg, 1 mg Source E. coli Species Human

CCL18/MIP4 Recombinant Protein - H00006362-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CCL18/PARC Partial Recombinant Protein - H00006362-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CCL18/PARC Recombinant Protein - P3655 from Novus Biologicals Category Protein Prices $369.00 Sizes 25 µg Species Human

Recombinant Human CCL18/PARC Protein - NBP1-99398 from Novus Biologicals Category Protein Prices $190.00 Sizes 10 µg Source E. coli Species Human

Recombinant Human CCL18/PARC Protein - NBP1-50937 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 10 µg, 50 µg Source E. coli Species Human

MIP4 recombinant protein - GTX65246 from GeneTex Category Protein Prices $249.00 Sizes 10 μg Source E. coli Species Human

MIP4 Recombinant Protein (Active) - GTX48368-PRO from GeneTex Category Protein Prices $299.00 Sizes 10 μg Source E. coli Species Human

PARC Peptide - GTX85085-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Recombinant Human CCL18/PARC - 394-PA-010 from R&D Systems Category Protein Source E. coli-derived, Ala21-Ala89

Recombinant Human CCL18/PARC - 394-PA-050 from R&D Systems Category Protein Source E. coli-derived, Ala21-Ala89

Recombinant Human CCL18/PARC, CF - 394-PA-010/CF from R&D Systems Category Protein Source E. coli-derived, Ala21-Ala89

Recombinant Human CCL18/PARC, CF - 394-PA-050/CF from R&D Systems Category Protein Source E. coli-derived, Ala21-Ala89

Recombinant human C-C motif chemokine 18 (OPCA01218) - OPCA01218 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

MIP 4 Protein (OPPA00420) - OPPA00420 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

MIP 4 Protein (OPPA02546) - OPPA02546 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 1 µg Source E. Coli

Human MIP-4 Protein (OPSA11003) - OPSA11003 from Aviva Systems Biology Category Protein Prices $430.00 Sizes 10 µg Species Human

Recombinant MIP-4 / CCL18 (OPSD00072) - OPSD00072 from Aviva Systems Biology Category Protein Prices $105.00 Sizes 2 µg

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