CCL18

Gene Symbol	CCL18
Entrez Gene	6362
Alt Symbol	AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
Other Description	C-C motif chemokine 18|CC chemokine PARC|CC chemokine ligand 18|alternative macrophage activation-associated CC chemokine 1|chemokine (C-C), dendritic|dendritic cell chemokine 1|macrophage inflammatory protein 4|pulmonary and activation-regulated chemokine|small inducible cytokine A18|small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated|small-inducible cytokine A18
Swissprots	Q53X71 P55774 B5BUM2
Accessions	AAC32287 AAD30390 BAA34368 CAJ15096 EAW80102 P55774 AB000221 BAA21670 AB451458 BAG70272 BC069700 AAH69700 BC096124 AAH96124 BC096125 AAH96125 BC096126 AAH96126 BC096127 AAH96127 BU617136 CR407660 CAG28588 HQ448456 ADQ32936 Y13710 CAA74039 NM_002988 NP_002979
Function	Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. {ECO:0000269|PubMed:11745396, ECO:0000269|PubMed:11978786}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid. {ECO:0000269|PubMed:11745396}.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MIP-4 (A-7) - sc-374438 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

MIP-4 (C-20) - sc-9781 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

MIP-4 (H-12) - sc-374439 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Anti-Macrophage Inflammatory Protein 4 antibody - ab104867 from Abcam Prices $370.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-Macrophage Inflammatory Protein 4 antibody - ab9849 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Macrophage Inflammatory Protein 4 antibody (Biotin) - ab17492 from Abcam Host Rabbit Clonality Polyclonal

Anti-Macrophage Inflammatory Protein 4 antibody [MM0142-7N58] - ab89338 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone MM0142-7N58

Anti-CCL18 / PARC Antibody (Biotin) - LS-C104368 from LifeSpan Bioscience Prices $285.00, $325.00 Sizes 25 µg, 50 µg Host Rabbit Clonality Polyclonal

Anti-CCL18 / PARC Antibody (aa21-89, Biotin) - LS-C300059 from LifeSpan Bioscience Prices $335.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL18 / PARC Antibody - LS-C104536 from LifeSpan Bioscience Prices $285.00, $325.00 Sizes 50 µg, 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL18 / PARC Antibody (aa21-89, FITC) - LS-C304330 from LifeSpan Bioscience Prices $345.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL18 / PARC Antibody - LS-C309754 from LifeSpan Bioscience Prices $475.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CCL18 / PARC Antibody - LS-C309768 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL18 / PARC Antibody (aa25-89) - LS-C311648 from LifeSpan Bioscience Prices $250.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CCL18 / PARC Antibody (clone 2C6) - LS-C198167 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2C6

Anti-CCL18 / PARC Antibody (aa21-89) - LS-C296147 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL18 / PARC Antibody (aa21-89) - LS-C314248 from LifeSpan Bioscience Prices $365.00 Sizes 200 µg Host Mouse Clonality Monoclonal

Anti-CCL18 / PARC Antibody (aa21-89) - LS-C313416 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL18 / PARC Antibody (C-Terminus) IHC-plus™ - LS-B929 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

CCL18/PARC Antibody - AF394 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Goat Clonality Polyclonal

CCL18/PARC Antibody (64507) - MAB394 from Novus Biologicals Prices $99.00, $269.00, $699.00 Sizes 25 µg, 100 µg, 500 µg Host Mouse Clonality Monoclonal Clone 64507

CCL18/PARC Antibody - NBP1-79940 from Novus Biologicals Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PARC Antibody (PO69) - NB100-78463 from Novus Biologicals Prices $369.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone PO69

PARC Antibody - NB100-2300 from Novus Biologicals Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

CCL18/PARC Antibody (MM0142-7N58) - NBP2-12096 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone MM0142-7N58

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