CUL5

Gene Symbol	CUL5
Entrez Gene	8065
Alt Symbol	VACM-1, VACM1
Species	Human
Gene Type	protein-coding
Description	cullin 5
Other Description	CUL-5|Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1)|Vasopressin-activated calcium-mobilizing receptor-1|cullin-5|vasopressin-activated calcium-mobilizing receptor 1
Swissprots	A8K960 Q93034 Q9BZC6 O14766
Accessions	EAW67101 EAW67102 Q93034 AA099369 AA403092 AA471067 AF017061 AAB70253 AF327710 AAK07472 AK125294 AK292575 BAF85264 BC017838 BC037203 BC063306 AAH63306 H01402 X81882 CAA57465 XM_005271682 XP_005271739 XM_011543012 XP_011541314 XM_011543013 XP_011541315 NM_003478 NP_003469
Function	Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
Top Pathways	Ubiquitin mediated proteolysis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Cullin-5 (CUL5), Human, ELISA Kit - E01C2186 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 2.5-50ng/ml

Cullin-5 (CUL5), ELISA Kit - MBS7201030 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-5 (CUL5), ELISA Kit - MBS7238160 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-5 (CUL5), ELISA Kit - MBS7221280 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-5 (CUL5), ELISA Kit - MBS7234346 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-5 (CUL5), ELISA Kit - MBS7209041 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-5 (CUL5), ELISA Kit - MBS7216490 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-5 (CUL5), ELISA Kit - MBS7220115 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-5 (CUL5), ELISA Kit - MBS7228318 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-5 (CUL5), ELISA Kit - MBS7222179 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-5 (CUL5), ELISA Kit - MBS7201751 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin-5 (CUL5), ELISA Kit - MBS7219935 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin 5 (CUL5), ELISA Kit - MBS9312085 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cullin 5 (CUL5), ELISA Kit - MBS7250069 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human VACM-1 ELISA Kit - EKB01851 from Biomatik Category ELISA Kit Prices $527.00, $2,503.00, $4,848.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 50pg/ml Range 0.082-60ng/ml

Human CUL5 ELISA Kit - E010388 from Biobool Category ELISA Kit

VACM-1 (Cullin 5), ELISA Kit - MBS7606107 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

Cullin-5, ELISA Kit - MBS284482 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CUL5 ELISA Kit (Human) (OKWB00205) - OKWB00205 from Aviva Systems Biology Category ELISA Kit Sensitivity 0.094 ng/mL Range 0.156 - 10 ng/mL

Human CUL5 / Cullin-5 ELISA Kit (Sandwich ELISA) - LS-F31952 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.094 Range 0.156-10 ng/ml

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