CUL5

Gene Symbol CUL5
Entrez Gene 8065
Alt Symbol VACM-1, VACM1
Species Human
Gene Type protein-coding
Description cullin 5
Other Description CUL-5|Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1)|Vasopressin-activated calcium-mobilizing receptor-1|cullin-5|vasopressin-activated calcium-mobilizing receptor 1
Swissprots A8K960 Q93034 Q9BZC6 O14766
Accessions EAW67101 EAW67102 Q93034 AA099369 AA403092 AA471067 AF017061 AAB70253 AF327710 AAK07472 AK125294 AK292575 BAF85264 BC017838 BC037203 BC063306 AAH63306 H01402 X81882 CAA57465 XM_005271682 XP_005271739 XM_011543012 XP_011541314 XM_011543013 XP_011541315 NM_003478 NP_003469
Function Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
Top Pathways Ubiquitin mediated proteolysis

CUL-5 CRISPR/Cas9 KO Plasmid (h) - sc-401344 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUL-5 HDR Plasmid (h) - sc-401344-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUL-5 Double Nickase Plasmid (h) - sc-401344-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUL-5 Double Nickase Plasmid (h2) - sc-401344-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUL-5 CRISPR Activation Plasmid (h) - sc-401344-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUL-5 CRISPR Activation Plasmid (h2) - sc-401344-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUL-5 Lentiviral Activation Particles (h) - sc-401344-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUL-5 Lentiviral Activation Particles (h2) - sc-401344-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUL-5 siRNA (h) - sc-37574 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CUL-5 shRNA Plasmid (h) - sc-37574-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CUL-5 shRNA (h) Lentiviral Particles - sc-37574-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cullin 5 RNAi - H00008065-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU031301 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6777 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6777 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CUL5 siRNA (Human) - CRH5355 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CUL5 - MBS8227068 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CUL5 (NM_003478.3) - SHH271897 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CUL5(NM_003478.3) - SHG211633 from Creative biogene

Category siRNA
Species Reactivities Human

CUL5 shRNA Plasmid (Human) - CHH5355 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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