SOX7

Gene Symbol SOX7
Entrez Gene 83595
Alt Symbol -
Species Human
Gene Type protein-coding
Description SRY (sex determining region Y)-box 7
Other Description transcription factor SOX-7
Swissprots Q9BT81 B4DKV0 Q53YD0
Accessions Q9BT81 AJ409320 CAC84226 AK055556 BAB70955 AK223574 BAD97294 BC004299 BC071947 AAH71947 BE671627 BG740632 BT006693 AAP35339 BU187815 HY089489 NM_031439 NP_113627
Function Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'. {ECO:0000250, ECO:0000269|PubMed:18819930}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}. Cytoplasm {ECO:0000269|PubMed:18819930}.
Tissue Specificity Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation. {ECO:0000269|PubMed:11691915, ECO:0000269|PubMed:18819930}.

SOX7 - MBS1265794 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC071947

Human SOX7 cDNA clone(NM_031439.2) - CDFG005436 from Creative Biomart

Species Human
Accession NM_031439.2

Human SOX7 ORF Clone(NM_031439.2) - CDCL176698 from Creative Biomart

Species Human
Accession NM_031439.2

human SOX7 ORF clone - CDCH084648 from Creative Biomart

Species Human
Accession NM_031439

human SOX7 ORF clone - CDCH084649 from Creative Biomart

Species Human
Accession NM_031439

Human SOX7 ORF Clone(NM_031439.2) - CDCR311177 from Creative Biomart

Species Human
Accession NM_031439.2

Human SOX7 ORF Clone(NM_031439.2) - CDCR311178 from Creative Biomart

Species Human
Accession NM_031439.2

Human SOX7 ORF Clone(NM_031439.2) - CDCR311179 from Creative Biomart

Species Human
Accession NM_031439.2

Human SOX7 ORF Clone(NM_031439.2) - CDCR311177 from Creative biogene

Species Human

Human SOX7 ORF Clone (BC071947) - CDCS416086 from Creative biogene

Species Human
Accession Q9BT81

Human SOX7 ORF clone (BC071947) - CDCB159399 from Creative biogene

Species Human
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