SOX7

Gene Symbol SOX7
Entrez Gene 83595
Alt Symbol -
Species Human
Gene Type protein-coding
Description SRY (sex determining region Y)-box 7
Other Description transcription factor SOX-7
Swissprots Q9BT81 B4DKV0 Q53YD0
Accessions Q9BT81 AJ409320 CAC84226 AK055556 BAB70955 AK223574 BAD97294 BC004299 BC071947 AAH71947 BE671627 BG740632 BT006693 AAP35339 BU187815 HY089489 NM_031439 NP_113627
Function Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'. {ECO:0000250, ECO:0000269|PubMed:18819930}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}. Cytoplasm {ECO:0000269|PubMed:18819930}.
Tissue Specificity Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation. {ECO:0000269|PubMed:11691915, ECO:0000269|PubMed:18819930}.

Sox-7 CRISPR/Cas9 KO Plasmid (h) - sc-402935 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sox-7 HDR Plasmid (h) - sc-402935-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sox-7 Double Nickase Plasmid (h) - sc-402935-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sox-7 Double Nickase Plasmid (h2) - sc-402935-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sox-7 CRISPR Activation Plasmid (h) - sc-402935-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sox-7 CRISPR Activation Plasmid (h2) - sc-402935-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sox-7 Lentiviral Activation Particles (h) - sc-402935-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sox-7 Lentiviral Activation Particles (h2) - sc-402935-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sox-7 siRNA (h) - sc-38416 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sox-7 shRNA Plasmid (h) - sc-38416-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sox-7 shRNA (h) Lentiviral Particles - sc-38416-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SOX7 RNAi - H00083595-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU122021 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20362 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20362 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SOX7 siRNA (Human) - CRJ3137 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SOX7 - MBS8205115 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Sox-7 CRISPR/Cas9 KO Plasmid (h2) - sc-402935-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sox-7 HDR Plasmid (h2) - sc-402935-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human SOX7 (NM_031439.2) - SHH415480 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SOX7(NM_031439.2) - SHL017294 from Creative biogene

Category siRNA
Species Reactivities Human

SOX7 shRNA Plasmid (Human) - CHJ3137 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SOX7 miRNA 3'UTR clone - MiUTR1H-09772 from Creative biogene

Species Reactivities Human
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