SOX7

Gene Symbol	SOX7
Entrez Gene	83595
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	SRY (sex determining region Y)-box 7
Other Description	transcription factor SOX-7
Swissprots	Q9BT81 B4DKV0 Q53YD0
Accessions	Q9BT81 AJ409320 CAC84226 AK055556 BAB70955 AK223574 BAD97294 BC004299 BC071947 AAH71947 BE671627 BG740632 BT006693 AAP35339 BU187815 HY089489 NM_031439 NP_113627
Function	Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'. {ECO:0000250, ECO:0000269|PubMed:18819930}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}. Cytoplasm {ECO:0000269|PubMed:18819930}.
Tissue Specificity	Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation. {ECO:0000269|PubMed:11691915, ECO:0000269|PubMed:18819930}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SOX7 full length protein - ab132264 from Abcam Category Protein Source Wheat germ Species Human

Human SOX7 peptide - ab24405 from Abcam Category Peptide Species Human

SOX7 peptide - ab109648 from Abcam Category Peptide

SOX7 Antibody Blocking Peptide - LS-E4945 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOX7 Antibody Blocking Peptide - LS-E14377 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOX7 Antibody Blocking Peptide - LS-E14376 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SOX7 Protein - H00083595-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SOX7-Antibody-C-term-Blocking-Peptide - BP17335b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SOX7 Blocking Peptide - 33R-5140 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SOX7 Blocking Peptide - 33R-2017 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SOX7 Blocking Peptide - 33R-4965 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SOX7 - H00083595-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SOX7 - H00083595-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SOX7 fusion protein - ag11996 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SOX7 fusion protein - ag10323 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Transcription factor SOX-7(SOX7) - CSB-YP866278HU CSB-EP866278HU CSB-BP866278HU CSB-MP866278HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SOX7 (full length, N-term HIS tag) - TP760192 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

SOX7 Recombinant Protein Antigen - NBP1-86116PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SOX7-Blocking-Peptide-Center - BP21090a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SOX7-Blocking-Peptide-C-term - BP21030c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SOX7 Peptide, Human - M34GP14923H from Creative Peptides Category Peptide Source Synthetic. Species Human

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