SOX7

Gene Symbol	SOX7
Entrez Gene	83595
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	SRY (sex determining region Y)-box 7
Other Description	transcription factor SOX-7
Swissprots	Q9BT81 B4DKV0 Q53YD0
Accessions	Q9BT81 AJ409320 CAC84226 AK055556 BAB70955 AK223574 BAD97294 BC004299 BC071947 AAH71947 BE671627 BG740632 BT006693 AAP35339 BU187815 HY089489 NM_031439 NP_113627
Function	Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'. {ECO:0000250, ECO:0000269\|PubMed:18819930}.
Subcellular Location	Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00267}. Cytoplasm {ECO:0000269\|PubMed:18819930}.
Tissue Specificity	Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation. {ECO:0000269\|PubMed:11691915, ECO:0000269\|PubMed:18819930}.

Sox-7 (H-175) - sc-20093 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Sox-7 (H-175): sc-20093. Western blot analysis of Sox-7 expression in U-937 (A) and PC-3 (B) nuclear extracts.

Sox-7 (E-20) - sc-17333 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-SOX7 antibody - ab80331 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 antibody (ab80331) at 1 µg/ml + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-SOX7 antibody - ab49163 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 antibody (ab49163) at 1.25 µg/ml + SP2/0 lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50,000 -1/100,000 dilution

Anti-SOX7 antibody - ab182761 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 antibody (ab182761) at 1/750 dilution + Human lymphoma tissue at 40 µgSecondaryGoat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutiondeveloped using the ECL technique

Anti-SOX7 antibody - ab89954 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 antibody (ab89954) at 1 µg/ml + Human fetal stomach lysate at 10 µgSecondaryHRP-conjugated Goat anti-Rabbit IgG at 1/50000 dilution

Anti-SOX7 antibody - ab94397 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 antibody (ab94397) at 1 µg/ml + Heart (Human) Tissue Lysate - adult normal tissue (ab29431) at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-SOX7 Antibody (aa249-345, PE) - LS-C144190 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 tst
Host	Goat
Clonality	Polyclonal

Anti-SOX7 Antibody (aa148-162) - LS-C147967 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 Antibody (aa107-126) - LS-C148863 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 Antibody (aa309-339, AP) - LS-C270025 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 Antibody (N-Terminus) - LS-C30909 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 Antibody (C-Terminus) - LS-C110424 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

SOX7 antibody Western Blot of Fetal Stomach cell lysate.

Anti-SOX7 Antibody (aa309-339, APC) - LS-C270026 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 Antibody (aa309-339, Biotin) - LS-C270027 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 Antibody (aa309-339, FITC) - LS-C270028 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 Antibody (aa309-339, PE) - LS-C270030 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 Antibody (aa309-339, Azide-free, HRP) - LS-C270029 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 Antibody (aa309-339) - LS-C325289 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 Antibody (aa310-339) - LS-C159065 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

SOX7 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The SOX7 antibody detected the SOX7 protein (arrow).

Anti-SOX7 Antibody (aa370-388) - LS-C313380 from LifeSpan Bioscience

Prices	$305.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

WB of SOX7 antibody. All lanes: Anti-SOX7 at 0.5ug/ml. Lane 1: Rat Brain Tissue Lysate at 40ug. Lane 2: Human Placenta Tissue Lysate at 40ug. Lane 3: Rat Lung Tissue Lysate at 40ug. Lane 4: Rat Testis Tissue Lysate at 40ug. Lane 5: HELA Whole Cell Lysate at 40ug. Lane 6: A549 Whole Cell Lysate at 40ug. Lane 7: HEPG2 Whole Cell Lysate at 40ug. Lane 8: SMMC Whole Cell Lysate at 40ug. Lane 9: NEURO Whole Cell Lysate at 40ug. Predicted bind size: 42KD. Observed bind size: 42KD.

Anti-SOX7 Antibody (aa38-87) IHC-plus™ - LS-B4005 from LifeSpan Bioscience

Prices	$450.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SOX7 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4005 concentration 5 ug/ml.

SOX7 Antibody [Unconjugated] - AF2766 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Goat
Clonality	Polyclonal

SOX7 Antibody - NBP1-80373 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: SOX7 Antibody [NBP1-80373] - Transfected 293T, Antibody Titration: 0.2-1 ug/ml

SOX7 Antibody (288610) - MAB2766 from Novus Biologicals

Prices	$99.00, $249.00
Sizes	25 µg, 100 µg
Host	Mouse
Clonality	Monoclonal
Clone	288610

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