Gene Symbol | CES3 |
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Entrez Gene | 23491 |
Alt Symbol | ES31 |
Species | Human |
Gene Type | protein-coding |
Description | carboxylesterase 3 |
Other Description | carboxylesterase 3 (brain)|esterase 31|liver carboxylesterase 31 homolog |
Swissprots | Q9H6X7 Q7Z6J1 B2Z3W9 F5H242 Q6UWW8 |
Accessions | ACD11491 EAW83060 EAW83062 Q6UWW8 AK000105 AK025158 AK025171 AK025389 BAB15123 AK097538 BAC05093 AY358609 AAQ88972 BC053670 AAH53670 DA924627 XM_011522975 XP_011521277 XM_011522976 XP_011521278 NM_001185176 NP_001172105 NM_001185177 NP_001172106 NM_024922 NP_079198 NM_012122 |
Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)- 1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000250}. |
Tissue Specificity | Expressed in liver, colon and small intestine. {ECO:0000269|PubMed:14581373, ECO:0000269|PubMed:15100172, ECO:0000269|PubMed:15687373}. |
CES3 (F-15) - sc-160234 from Santa Cruz Biotechnology
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CES3 (N-14) - sc-160235 from Santa Cruz Biotechnology
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Anti-Carboxylesterase 3 / CES3 Antibody - LS-C306908 from LifeSpan Bioscience
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Anti-Carboxylesterase 3 / CES3 Antibody (aa260-309) - LS-C151468 from LifeSpan Bioscience
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Anti-Carboxylesterase 3 / CES3 Antibody (C-Terminus) - LS-C145673 from LifeSpan Bioscience
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Carboxylesterase 3/CES3/Esterase 31 Antibody - NBP1-98271 from Novus Biologicals
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Carboxylesterase 3/CES3/Esterase 31 Antibody - H00023491-B01P from Novus Biologicals
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Anti-CES3 antibody produced in rabbit - HPA041008 from Sigma-Aldrich
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Anti-CES3 antibody produced in rabbit - SAB2107671 from Sigma-Aldrich
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Anti-CES3 antibody produced in rabbit - HPA041307 from Sigma-Aldrich
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Anti-CES3 antibody produced in mouse - SAB1407217 from Sigma-Aldrich
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CES3 antibody - C-terminal region (ARP62006_P050) - ARP62006_P050 from Aviva Systems Biology
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CES3 antibody - middle region (ARP62007_P050) - ARP62007_P050 from Aviva Systems Biology
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Mouse/Rat Carboxylesterase 3/CES3 Antibody - AF5985 from R&D Systems
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Mouse/Rat Carboxylesterase 3/CES3 Affinity Purified PAb, Goat IgG - AF5985-SP from R&D Systems
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CES3 antibody - 70R-10409 from Fitzgerald
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Anti -CES3 (Carboxylesterase 3, ES31) - 210102 from USBiological Life Science
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Anti -CES3 (Carboxylesterase 3, Liver Carboxylesterase 31 Homolog, UNQ869/PRO1887) - 124882 from USBiological Life Science
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CES3 Polyclonal Antibody - A4558 from ABclonal
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CES3 antibody - 70R-16362 from Fitzgerald
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CES3 Antibody - abx003421 from Abbexa
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CES3 antibody - 14587-1-AP from Acris Antibodies
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CES3 antibody - H00023491-B01P from Acris Antibodies
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Anti-CES3, Polyclonal Antibody - 25-A4558 from ARP American Research Products
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CES3 antibody - 14587-1-AP from Proteintech Group
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