CES3

Gene Symbol CES3
Entrez Gene 23491
Alt Symbol ES31
Species Human
Gene Type protein-coding
Description carboxylesterase 3
Other Description carboxylesterase 3 (brain)|esterase 31|liver carboxylesterase 31 homolog
Swissprots Q9H6X7 Q7Z6J1 B2Z3W9 F5H242 Q6UWW8
Accessions ACD11491 EAW83060 EAW83062 Q6UWW8 AK000105 AK025158 AK025171 AK025389 BAB15123 AK097538 BAC05093 AY358609 AAQ88972 BC053670 AAH53670 DA924627 XM_011522975 XP_011521277 XM_011522976 XP_011521278 NM_001185176 NP_001172105 NM_001185177 NP_001172106 NM_024922 NP_079198 NM_012122
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)- 1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000250}.
Tissue Specificity Expressed in liver, colon and small intestine. {ECO:0000269|PubMed:14581373, ECO:0000269|PubMed:15100172, ECO:0000269|PubMed:15687373}.

Human CES3 ORF Clone(NM_024922.5) - CDCL158610 from Creative Biomart

Species Human
Accession NM_024922.5

Human CES3 ORF Clone(NM_001185176.1) - CDCR357834 from Creative Biomart

Species Human
Accession NM_001185176.1

Human CES3 ORF Clone(NM_001185176.1) - CDCR357835 from Creative Biomart

Species Human
Accession NM_001185176.1

Human CES3 ORF Clone(NM_001185177.1) - CDCR357836 from Creative Biomart

Species Human
Accession NM_001185177.1

Human CES3 ORF Clone(NM_001185177.1) - CDCR357838 from Creative Biomart

Species Human
Accession NM_001185177.1

Human CES3 ORF Clone(NM_001185177.1) - CDCR357836 from Creative biogene

Species Human

Human CES3 ORF clone (NM_001185176.1) - CDCR046252 from Creative biogene

Species Human
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