RILP

Gene Symbol RILP
Entrez Gene 83547
Alt Symbol PP10141
Species Human
Gene Type protein-coding
Description Rab interacting lysosomal protein
Other Description rab-interacting lysosomal protein
Swissprots Q9BYS3 B2RBQ8 Q71RE6 Q96NA2 Q9BSL3
Accessions EAW90595 Q96NA2 AF370391 AAQ15227 AJ278711 CAC82174 AJ404317 CAC33443 AK055755 BAB71003 AK314767 BAG37305 BC004961 AAH04961 BC031621 AAH31621 DQ892467 ABM83393 DQ895680 ABM86606 XM_005256811 XP_005256868 XM_006725257 XP_006725320 NM_031430 NP_113618
Function Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes. {ECO:0000269|PubMed:11179213, ECO:0000269|PubMed:11696325, ECO:0000269|PubMed:12944476, ECO:0000269|PubMed:14668488}.
Subcellular Location Endomembrane system. Late endosome membrane. Lysosome membrane. Cytoplasmic vesicle, phagosome membrane. Note=Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7A is necessary for its recruitment to phagosomes.
Tissue Specificity Ubiquitous. Strongly expressed in fetal heart, heart, stomach, spleen, adrenal gland, thyroid gland, salivary gland, fetal liver, liver and lung. Poorly expressed in brain. {ECO:0000269|PubMed:11179213, ECO:0000269|PubMed:11520070, ECO:0000269|PubMed:14668488}.
Top Pathways Phagosome, Salmonella infection

RILP (E-18) - sc-82746 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RILP (E-18): sc-82746. Western blot analysis of RILP expression in NCI-H226 (A) and A549 (B) whole cell lysates.

RILP (H-85) - sc-98331 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RILP (H-85): sc-98331. Immunoperoxidase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing cytoplasmic staining of glandular cells.

Anti-RILP antibody - ab140188 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of RILP in HeLa cells with ab140188 at 20 ug/mL.

Anti-RILP antibody - ab128616 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab128616 stained MCF7 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab128616, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-RILP antibody - ab174737 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded sections of Human adrenal tissue  labeling RILP with ab174737 at  5 µg/ml.

Anti-RILP antibody - ab54559 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RILP antibody (ab54559) at 1 µg/ml + HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Anti-RILP Antibody (C-Terminus) - LS-C151640 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RILP antibody Western Blot of Placenta.

Anti-RILP Antibody (C-Terminus) - LS-C151641 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RILP antibody Western Blot of NCI-H226.

Anti-RILP Antibody (Internal) IHC-plus™ - LS-B8816 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RILP antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-RILP Antibody (C-Terminus) - LS-C47018 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

RILP Antibody - NBP2-13233 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: RILP Antibody [NBP2-13233] Staining of human adrenal gland shows strong membranous and cytoplasmic positivity in glandular cells.

RILP Antibody - NBP1-98279 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

RILP Antibody - NBP1-98278 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RILP antibody produced in rabbit - HPA052041 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RILP:<B>Cat. No. HPA052041</B>: Immunohistochemical staining of human adrenal gland shows strong membranous and cytoplasmic positivity in glandular cells.

Anti-RILP antibody produced in rabbit - SAB2107831 from Sigma-Aldrich

Prices $341.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RILP: <B>Cat. No. SAB2107831</B>: Western blot analysis of RILP with RILP (Rab interacting lysosomal protein) antibody against the C-terminal of RILP (50 μg) antibody at 1.0 μg/mL.

RILP antibody - C-terminal region (ARP64148_P050) - ARP64148_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RILP antibody - C-terminal region (ARP64149_P050) - ARP64149_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RILP antibody - orb75778 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of HeLa cell lysate at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide using RILP antibody

RILP antibody - 13574-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of HepG2 cells using 13574-1-AP( RILP Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

RILP (Center) antibody - AP55644PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of RILP in HeLa cells with RILP antibody at 2.5 ug/mL.

RILP antibody - PAB5557 from Acris Antibodies

Prices $420.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Human RILP (Internal) - 119-17319 from RayBiotech

Host Rabbit

RILP Antibody - 6791 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of RILP in A20 cell lysate with RILP antibody at 1 μg/mL.

RILP antibody - 13574-1-AP from Proteintech Group

Prices $279.00
Sizes con: 87 μg/150μl
Host Rabbit
Clonality Polyclonal
HEK-293 cells were subjected to SDS PAGE followed by western blot with 13574-1-AP( RILP Antibody) at dilution of 1:300

RILP Antibody - 25472 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of RILP in HeLa cell lysate with RILP antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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