RILP

Gene Symbol RILP
Entrez Gene 83547
Alt Symbol PP10141
Species Human
Gene Type protein-coding
Description Rab interacting lysosomal protein
Other Description rab-interacting lysosomal protein
Swissprots Q9BYS3 B2RBQ8 Q71RE6 Q96NA2 Q9BSL3
Accessions EAW90595 Q96NA2 AF370391 AAQ15227 AJ278711 CAC82174 AJ404317 CAC33443 AK055755 BAB71003 AK314767 BAG37305 BC004961 AAH04961 BC031621 AAH31621 DQ892467 ABM83393 DQ895680 ABM86606 XM_005256811 XP_005256868 XM_006725257 XP_006725320 NM_031430 NP_113618
Function Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes. {ECO:0000269|PubMed:11179213, ECO:0000269|PubMed:11696325, ECO:0000269|PubMed:12944476, ECO:0000269|PubMed:14668488}.
Subcellular Location Endomembrane system. Late endosome membrane. Lysosome membrane. Cytoplasmic vesicle, phagosome membrane. Note=Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7A is necessary for its recruitment to phagosomes.
Tissue Specificity Ubiquitous. Strongly expressed in fetal heart, heart, stomach, spleen, adrenal gland, thyroid gland, salivary gland, fetal liver, liver and lung. Poorly expressed in brain. {ECO:0000269|PubMed:11179213, ECO:0000269|PubMed:11520070, ECO:0000269|PubMed:14668488}.
Top Pathways Phagosome, Salmonella infection

Rab interacting lysosomal protein, ELISA Kit - MBS9331400 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human RILP ELISA Kit - E032635 from Biobool

Category ELISA Kit
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