RILP

Gene Symbol RILP
Entrez Gene 83547
Alt Symbol PP10141
Species Human
Gene Type protein-coding
Description Rab interacting lysosomal protein
Other Description rab-interacting lysosomal protein
Swissprots Q9BYS3 B2RBQ8 Q71RE6 Q96NA2 Q9BSL3
Accessions EAW90595 Q96NA2 AF370391 AAQ15227 AJ278711 CAC82174 AJ404317 CAC33443 AK055755 BAB71003 AK314767 BAG37305 BC004961 AAH04961 BC031621 AAH31621 DQ892467 ABM83393 DQ895680 ABM86606 XM_005256811 XP_005256868 XM_006725257 XP_006725320 NM_031430 NP_113618
Function Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes. {ECO:0000269|PubMed:11179213, ECO:0000269|PubMed:11696325, ECO:0000269|PubMed:12944476, ECO:0000269|PubMed:14668488}.
Subcellular Location Endomembrane system. Late endosome membrane. Lysosome membrane. Cytoplasmic vesicle, phagosome membrane. Note=Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7A is necessary for its recruitment to phagosomes.
Tissue Specificity Ubiquitous. Strongly expressed in fetal heart, heart, stomach, spleen, adrenal gland, thyroid gland, salivary gland, fetal liver, liver and lung. Poorly expressed in brain. {ECO:0000269|PubMed:11179213, ECO:0000269|PubMed:11520070, ECO:0000269|PubMed:14668488}.
Top Pathways Phagosome, Salmonella infection

RILP Antibody Blocking Peptide - LS-E23395 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RILP Antibody Blocking Peptide - LS-E23394 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RILP Antibody Blocking Peptide - LS-E31257 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

RILP (Center) Control Peptide - AP55644CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg
Western blot analysis in HeLa cell lysate with RILP antibody Cat.-No. AP55644CP-N at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

RILP Peptide - 6791P from ProSci

Category Peptide
Species Human
Western blot analysis of RILP in HeLa cell lysate with RILP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

RILP fusion protein - Ag4472 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, T-HIS
Species Human

Recombinant Human RILP, His-tagged - RILP-2303H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Rab-interacting lysosomal protein(RILP) - CSB-YP850399HU CSB-EP850399HU CSB-BP850399HU CSB-MP850399HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

RILP - TP306400 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
RILP

RILP Protein - NBP2-13233PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

RILP Peptide, Human - M34GP13301H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Rab-interacting lysosomal protein (RILP), Recombinant Protein - MBS1317365 from MyBioSource

Category Protein
Prices $1,175.00, $1,175.00, $1,390.00, $1,390.00, $1,885.00, $1,885.00, $2,345.00, $2,345.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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