PACSIN3

Gene Symbol PACSIN3
Entrez Gene 29763
Alt Symbol SDPIII
Species Human
Gene Type protein-coding
Description protein kinase C and casein kinase substrate in neurons 3
Other Description SH3 domain-containing protein 6511|protein kinase C and casein kinase substrate in neurons protein 3|syndapin III
Swissprots Q9H331 Q9NWV9 Q9UKS6 A6NH84
Accessions EAW67960 EAW67961 EAW67962 Q9UKS6 AB528520 BAI46684 AF130979 AAF04472 AF149825 AAG31023 AF242530 AAK29207 AK000577 BAA91267 AK300658 BAG62344 AK300968 BAG62592 AK310819 BC007914 AAH07914 BC011889 AAH11889 BI601317 DQ893156 ABM84082 DQ896450 ABM87449 NM_001184974 NP_001171903 NM_001184975 NP_001171904 NM_016223 NP_057307
Function Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11179684}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Detected at the inner aspect of the plasma membrane in myotubes. {ECO:0000250}.
Tissue Specificity Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney. {ECO:0000269|PubMed:11082044, ECO:0000269|PubMed:11179684}.

PACSIN3 CRISPR/Cas9 KO Plasmid (h) - sc-416241 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PACSIN3 HDR Plasmid (h) - sc-416241-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PACSIN3 Double Nickase Plasmid (h) - sc-416241-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PACSIN3 Double Nickase Plasmid (h2) - sc-416241-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PACSIN3 CRISPR Activation Plasmid (h) - sc-416241-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PACSIN3 CRISPR Activation Plasmid (h2) - sc-416241-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PACSIN3 Lentiviral Activation Particles (h) - sc-416241-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PACSIN3 Lentiviral Activation Particles (h2) - sc-416241-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PACSIN3 siRNA (h) - sc-61279 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PACSIN3 shRNA Plasmid (h) - sc-61279-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PACSIN3 shRNA (h) Lentiviral Particles - sc-61279-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PACSIN3 RNAi - H00029763-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU130761 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16263 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16263 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03254 from Sigma-Aldrich

Category miRNA

PACSIN3 siRNA (Human) - CRH9219 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PACSIN3 (NM_016223.4) - SHH369912 from Creative biogene

Category siRNA
Species Reactivities Human

Human PACSIN3 siRNA - orb269721 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PACSIN3 shRNA Plasmid (Human) - CHH9219 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PACSIN3 miRNA 3'UTR clone - MiUTR3H-08523 from Creative biogene

Species Reactivities Human
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