PACSIN3

Gene Symbol PACSIN3
Entrez Gene 29763
Alt Symbol SDPIII
Species Human
Gene Type protein-coding
Description protein kinase C and casein kinase substrate in neurons 3
Other Description SH3 domain-containing protein 6511|protein kinase C and casein kinase substrate in neurons protein 3|syndapin III
Swissprots Q9H331 Q9NWV9 Q9UKS6 A6NH84
Accessions EAW67960 EAW67961 EAW67962 Q9UKS6 AB528520 BAI46684 AF130979 AAF04472 AF149825 AAG31023 AF242530 AAK29207 AK000577 BAA91267 AK300658 BAG62344 AK300968 BAG62592 AK310819 BC007914 AAH07914 BC011889 AAH11889 BI601317 DQ893156 ABM84082 DQ896450 ABM87449 NM_001184974 NP_001171903 NM_001184975 NP_001171904 NM_016223 NP_057307
Function Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11179684}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Detected at the inner aspect of the plasma membrane in myotubes. {ECO:0000250}.
Tissue Specificity Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney. {ECO:0000269|PubMed:11082044, ECO:0000269|PubMed:11179684}.

PACSIN3 (C-3) - sc-166923 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PACSIN3 (C-3): sc-166923. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

PACSIN3 (F-8) - sc-373952 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PACSIN3 (F-8): sc-373952. Western blot analysis of PACSIN3 expression in non-transfected: sc-117752 (A) and mouse PACSIN3 transfected: sc-127289 (B) 293T whole cell lysates.

PACSIN3 (H-100) - sc-99128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PACSIN3 (H-100): sc-99128. Western blot analysis of PACSIN3 expression in non-transfected 293T: sc-117752 (A), mouse PACSIN3 transfected 293T: sc-127289 (B) and HeLa (C) whole cell lysates.

PACSIN3 (N-15) - sc-48257 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PACSIN3 (K-16) - sc-48255 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PACSIN3 (K-16): sc-48255. Western blot analysis of PACSIN3 expression in non-transfected: sc-117752 (A) and mouse PACSIN3 transfected: sc-127289 (B) 293T whole cell lysates.

PACSIN3 (C-12) - sc-48254 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PACSIN3 antibody - ab37612 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-PACSIN3 antibody - ab2226 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot staining for ab2226 (1µg/ml) of H460 lysate (35µg total protein per lane). Primary incubated for 1 hour.

Anti-PACSIN3 antibody - ab86077 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PACSIN3 antibody (ab86077) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µg

Anti-PACSIN3 antibody [4F8] - ab123913 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4F8
All lanes : Anti-PACSIN3 antibody [4F8] (ab123913) at 1/1000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cells transfected with pCMV6-ENTRY PACSIN3 cDNA Lysates/proteins at 5 µg per lane.

Anti-PACSIN3 antibody [EPR16138] - ab192875 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16138
All lanes : Anti-PACSIN3 antibody [EPR16138] (ab192875) at 1/10000 dilutionLane 1 : Human heart lysateLane 2 : HepG2 cell lysateLane 3 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-PACSIN3 antibody - N-terminal - ab154101 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PACSIN3 antibody - N-terminal (ab154101) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-PACSIN3 Antibody (aa1-30) - LS-C101185 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-PACSIN3 Antibody (N-Terminus, AP) - LS-C245212 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACSIN3 Antibody (N-Terminus, APC) - LS-C245213 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACSIN3 Antibody (clone 2A6) - LS-C172530 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A6
Western blot of extracts (35 ug) from 9 different cell lines by using anti-PACSIN3 monoclonal antibody.

Anti-PACSIN3 Antibody (clone 2E4) - LS-C172529 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E4
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-PACSIN3 mouse monoclonal antibody.

Anti-PACSIN3 Antibody (clone 4A7) - LS-C172532 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4A7
Western blot of extracts (35 ug) from 9 different cell lines by using anti-PACSIN3 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

Anti-PACSIN3 Antibody (N-Terminus, Biotin) - LS-C245214 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACSIN3 Antibody (clone 4G7) - LS-C172531 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4G7
Western blot of extracts (35 ug) from 9 different cell lines by using anti-PACSIN3 monoclonal antibody.

Anti-PACSIN3 Antibody (clone 4C5) - LS-C172548 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4C5
Western blot of extracts (35 ug) from 9 different cell lines by using anti-PACSIN3 monoclonal antibody.

Anti-PACSIN3 Antibody (N-Terminus, FITC) - LS-C245215 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACSIN3 Antibody (N-Terminus, Azide-free, HRP) - LS-C247739 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACSIN3 Antibody (N-Terminus, PE) - LS-C245216 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PACSIN3 Antibody (aa275-325) - LS-C288740 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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