BRD7

Gene Symbol BRD7
Entrez Gene 29117
Alt Symbol BP75, CELTIX1, NAG4
Species Human
Gene Type protein-coding
Description bromodomain containing 7
Other Description 75 kDa bromodomain protein|bromodomain-containing protein 7|protein CELTIX-1
Swissprots Q9BV48 Q8N2L9 Q96KA4 Q4VC09 Q9UH59 Q9NPI1
Accessions EAW82756 EAW82757 EAW82758 EAW82759 Q9NPI1 AF152604 AAF75126 AF213969 AAF19526 AJ271881 CAB72445 AK027308 BAB55031 AK074613 BAC11089 AW615116 BC001611 AAH01611 BC050728 AAH50728 BC094706 AAH94706 CD677718 DA645362 XM_011523046 XP_011521348 XM_011523047 XP_011521349 XM_011523048 XP_011521350 XM_011523049 XP_011521351 XM_011523050 XP_011521352 XR_933289 XR_933290 XR_933291 NM_001173984 NP_001167455 NM_013263 NP_037395
Function Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase. {ECO:0000250, ECO:0000269|PubMed:16265664, ECO:0000269|PubMe
Subcellular Location Isoform 2: Nucleus.

BRD7 (H-2) - sc-376179 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BRD7 (H-2): sc-376179. Western blot analysis of BRD7 expression in non-transfected 293T: sc-117752 (A), human BRD7 transfected 293T: sc-116362 (B) and Jurkat (C) whole cell lysates.

BRD7 (H-77) - sc-292257 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BRD7 (H-77): sc-292257. Western blot analysis of BRD7 expression in non-transfected: sc-117752 (A) and human BRD7 transfected: sc-116362 (B) 293Twhole cell lysates.

BRD7 (P-13) - sc-131878 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BRD7 (P-13): sc-131878. Immunoperoxidase staining of formalin fixed, paraffin-embedded human urinary bladder tissue showing cytoplasmic and nuclear staining of urothelial cells.

BRD7 (T-12) - sc-131879 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BRD7 (B-8) - sc-376180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BRD7 (B-8): sc-376180. Western blot analysis of BRD7 expression in non-transfected 293T: sc-117752 (A), human BRD7 transfected 293T: sc-116362 (B) and Jurkat (C) whole cell lysates.

Anti-BRD7 antibody - ab170073 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human prostate carcinoma tissue, labeling BRD7 with ab170073 at 1/100 dilution.

Anti-BRD7 antibody - ab114061 from Abcam

Prices $428.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab114061, at 1/250 dilution, staining BRD7 in formalin-fixed, paraffin-embedded Human Prostate carcinoma by Immunohistochemistry with DAB staining.

Anti-BRD7 antibody - ChIP Grade - ab56036 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BRD7 antibody - ChIP Grade (ab56036) at 0.2 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-BRD7 Antibody (aa77-106, Biotin) - LS-C233187 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BRD7 Antibody (aa77-106, APC) - LS-C233188 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BRD7 Antibody (aa77-106, AP) - LS-C233189 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BRD7 Antibody (aa77-106, FITC) - LS-C233190 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BRD7 Antibody (aa77-106, PE) - LS-C233191 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BRD7 Antibody (aa77-106, Azide-free, HRP) - LS-C249532 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BRD7 Antibody (aa76-107) - LS-C319870 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BRD7 Antibody - LS-C332053 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-BRD7 Antibody (aa77-106) - LS-C156858 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BRD7 Antibody western blot of mouse heart tissue lysates (35 ug/lane). The BRD7 antibody detected the BRD7 protein (arrow).

Anti-BRD7 Antibody (aa601-651) - LS-C289056 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human BRD7 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-BRD7 used at a dilution of 1:1000 (1 ug/ml).

Anti-BRD7 Antibody (aa601-651) - LS-C286869 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human BRD7 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-BRD7 used at a dilution of 1:250.

Anti-BRD7 Antibody (aa387-418) - LS-C344632 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from mouse lung tissue lysate with MOUSE Brd7 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35 ug.

Anti-BRD7 Antibody (C-Terminus) IHC-plus™ - LS-B925 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BRD7 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B925 concentration 10 ug/ml.

BRD7 Antibody - NBP1-28727 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: BRD7 Antibody [NBP1-28727] - Whole cell lysate from HeLa (5, 15 and 50 ug for WB) and 293T (T; 50 ug) cells. Antibody used at 0.4 ug/ml

BRD7 Antibody - H00029117-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: BRD7 Antibody [H00029117-B01] - analysis of BRD7 expression in transfected 293T cell line by BRD7 MaxPab polyclonal antibody. Lane 1: BRD7 transfected lysate (71.61 KDa). Lane 2: Non-transfected lysate.

BRD7 Polyclonal Antibody - bs-7779R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-BRD7 antibody produced in rat - SAB4200047 from Sigma-Aldrich

Prices $61.10, $397.50
Sizes 25 µl, 200 µl
Host Rat
Clonality Monoclonal
Clone BRM 2D3
<B>Immunoblotting</B><BR/>Lysates were separated on SDS-PAGE and probed with 1 μg/mL Rat Anti-BRD7 Clone: BRM 2D3 (<B>Cat. No. SAB4200047</B>). The antibody was developed using Rabbit Anti-RAT IgG-Peroxidase (<B>Cat. No. A9542</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. HeLa; 2. Jurkat; 3. NRK; 4. PC12; 5. Neuro-2A; 6. NS1; 7. MDBK; 8. MDCK; 9. COS7
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