BRD7

Gene Symbol BRD7
Entrez Gene 29117
Alt Symbol BP75, CELTIX1, NAG4
Species Human
Gene Type protein-coding
Description bromodomain containing 7
Other Description 75 kDa bromodomain protein|bromodomain-containing protein 7|protein CELTIX-1
Swissprots Q9BV48 Q8N2L9 Q96KA4 Q4VC09 Q9UH59 Q9NPI1
Accessions EAW82756 EAW82757 EAW82758 EAW82759 Q9NPI1 AF152604 AAF75126 AF213969 AAF19526 AJ271881 CAB72445 AK027308 BAB55031 AK074613 BAC11089 AW615116 BC001611 AAH01611 BC050728 AAH50728 BC094706 AAH94706 CD677718 DA645362 XM_011523046 XP_011521348 XM_011523047 XP_011521349 XM_011523048 XP_011521350 XM_011523049 XP_011521351 XM_011523050 XP_011521352 XR_933289 XR_933290 XR_933291 NM_001173984 NP_001167455 NM_013263 NP_037395
Function Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase. {ECO:0000250, ECO:0000269|PubMed:16265664, ECO:0000269|PubMe
Subcellular Location Isoform 2: Nucleus.

BRD7 CRISPR/Cas9 KO Plasmid (h) - sc-416299 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRD7 HDR Plasmid (h) - sc-416299-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRD7 Double Nickase Plasmid (h) - sc-416299-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRD7 Double Nickase Plasmid (h2) - sc-416299-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRD7 CRISPR Activation Plasmid (h) - sc-416299-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRD7 CRISPR Activation Plasmid (h2) - sc-416299-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRD7 Lentiviral Activation Particles (h) - sc-416299-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRD7 Lentiviral Activation Particles (h2) - sc-416299-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRD7 siRNA (h) - sc-92998 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BRD7 shRNA Plasmid (h) - sc-92998-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BRD7 shRNA (h) Lentiviral Particles - sc-92998-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BRD7 RNAi - H00029117-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU108271 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU111711 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4051 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4051 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00510 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00510

BRD7 siRNA (Human) - CRH9206 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BRD7 - MBS8228763 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BRD7 shRNA Plasmid (Human) - CHH9206 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BRD7 miRNA 3'UTR clone - MiUTR3H-13785 from Creative biogene

Species Reactivities Human
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