BRD7

Gene Symbol	BRD7
Entrez Gene	29117
Alt Symbol	BP75, CELTIX1, NAG4
Species	Human
Gene Type	protein-coding
Description	bromodomain containing 7
Other Description	75 kDa bromodomain protein|bromodomain-containing protein 7|protein CELTIX-1
Swissprots	Q9BV48 Q8N2L9 Q96KA4 Q4VC09 Q9UH59 Q9NPI1
Accessions	EAW82756 EAW82757 EAW82758 EAW82759 Q9NPI1 AF152604 AAF75126 AF213969 AAF19526 AJ271881 CAB72445 AK027308 BAB55031 AK074613 BAC11089 AW615116 BC001611 AAH01611 BC050728 AAH50728 BC094706 AAH94706 CD677718 DA645362 XM_011523046 XP_011521348 XM_011523047 XP_011521349 XM_011523048 XP_011521350 XM_011523049 XP_011521351 XM_011523050 XP_011521352 XR_933289 XR_933290 XR_933291 NM_001173984 NP_001167455 NM_013263 NP_037395
Function	Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase. {ECO:0000250, ECO:0000269|PubMed:16265664, ECO:0000269|PubMe
Subcellular Location	Isoform 2: Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BRD7 full length protein - ab132508 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human BRD7 peptide - ab73296 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

BRD7 Antibody Blocking Peptide - LS-E2436 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRD7 Antibody Blocking Peptide - LS-E14071 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BRD7 Protein - H00029117-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BRD7-Antibody-N-term-Blocking-peptide - BP13451a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BRD7 Blocking Peptide - 33R-4343 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BRD7 - H00029117-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

BRD7 - H00029117-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

BRD7 fusion protein - Ag3911 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

BRD7 fusion protein - ag18032 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

BRD7 fusion protein - ag1461 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant BRD7 (129-236) protein - 31381 from ActiveMotif Category Protein Prices $395.00, $2,600.00 Sizes 100 µg, 1 mg Source E. coli Species Human

Recombinant BRD7 (129-236) protein, GST tag - 31480 from ActiveMotif Category Protein Prices $395.00, $2,900.00 Sizes 100 µg, 1 mg Source E. coli Species Human

Recombinant Human BRD7, GST-tagged - BRD7-12H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human BRD7, GST-tagged - BRD7-13H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human BRD7, GST-tagged - BRD7-14H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Bromodomain-containing protein 7(BRD7) - CSB-YP865097HU CSB-EP865097HU CSB-BP865097HU CSB-MP865097HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BRD7 - TP308734 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

BRD7 Peptide, Human - M34GP01529H from Creative Peptides Category Peptide Source Synthetic. Species Human

BRD7 Recombinant Protein Antigen - NBP2-55751PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BRD7 Recombinant Protein Antigen - NBP2-59009PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Bromodomain-containing protein 7 (BRD7), Recombinant Protein - MBS1377681 from MyBioSource Category Protein Prices $1,450.00, $1,450.00, $1,680.00, $1,680.00, $2,460.00, $2,460.00, $2,905.00, $2,905.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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