BMP10

Gene Symbol BMP10
Entrez Gene 27302
Alt Symbol -
Species Human
Gene Type protein-coding
Description bone morphogenetic protein 10
Other Description -
Swissprots Q53R17 O95393 Q6NTE0
Accessions AAY15075 EAW99863 O95393 AF101441 AAC77462 BC069080 AAH69080 BC101734 AAI01735 BC105063 AAI05064 NM_014482 NP_055297
Function Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines. {ECO:0000269|PubMed:16049014, ECO:0000269|PubMed:17068149, ECO:0000269|PubMed:20608934}.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Detected in mammary epithelia (at protein level). {ECO:0000269|PubMed:20608934}.

BMP10 293T Cell Transient Overexpression Lysate(Denatured) - H00027302-T02 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

BMP10 293T Cell Transient Overexpression Lysate(Denatured) - H00027302-T04 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

BMP10 overexpression lysate - LY415241 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

BMP10 293 Cell Lysate - 407180 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg
Tissue Bone

BMP-10 Overexpression Lysate (Native) - NBP2-07325 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: BMP10 Overexpression Lysate (Adult Normal) [NBP2-07325] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for BMP10.

BMP10 Over-expression Lysate Product - GWB-C6E935 from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

BMP-10 Overexpression Lysate (Denatured) - H00027302-T02 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

BMP-10 Overexpression Lysate (Denatured) - H00027302-T04 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human BMP10 Knockdown Stable Cell Line - CSC-DC001468 from Creative biogene

Category Cell Line
Species Human
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