BMP10

Gene Symbol BMP10
Entrez Gene 27302
Alt Symbol -
Species Human
Gene Type protein-coding
Description bone morphogenetic protein 10
Other Description -
Swissprots Q53R17 O95393 Q6NTE0
Accessions AAY15075 EAW99863 O95393 AF101441 AAC77462 BC069080 AAH69080 BC101734 AAI01735 BC105063 AAI05064 NM_014482 NP_055297
Function Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines. {ECO:0000269|PubMed:16049014, ECO:0000269|PubMed:17068149, ECO:0000269|PubMed:20608934}.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Detected in mammary epithelia (at protein level). {ECO:0000269|PubMed:20608934}.

BMP-10 CRISPR/Cas9 KO Plasmid (h) - sc-404729 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMP-10 HDR Plasmid (h) - sc-404729-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMP-10 Double Nickase Plasmid (h) - sc-404729-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMP-10 Double Nickase Plasmid (h2) - sc-404729-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMP-10 CRISPR Activation Plasmid (h) - sc-404729-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMP-10 CRISPR Activation Plasmid (h2) - sc-404729-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMP-10 Lentiviral Activation Particles (h) - sc-404729-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMP-10 Lentiviral Activation Particles (h2) - sc-404729-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMP-10 siRNA (h) - sc-39758 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BMP-10 shRNA Plasmid (h) - sc-39758-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BMP-10 shRNA (h) Lentiviral Particles - sc-39758-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU020891 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3998 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3998 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BMP10 siRNA (Human) - CRH9068 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BMP10 - MBS8213106 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BMP10 (NM_014482.1) - SHH247010 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BMP10(NM_014482.1) - SHG101851 from Creative biogene

Category siRNA
Species Reactivities Human

BMP10 shRNA Plasmid (Human) - CHH9068 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BMP10 miRNA 3'UTR clone - MiUTR1H-00906 from Creative biogene

Species Reactivities Human
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