BMP10

Gene Symbol BMP10
Entrez Gene 27302
Alt Symbol -
Species Human
Gene Type protein-coding
Description bone morphogenetic protein 10
Other Description -
Swissprots Q53R17 O95393 Q6NTE0
Accessions AAY15075 EAW99863 O95393 AF101441 AAC77462 BC069080 AAH69080 BC101734 AAI01735 BC105063 AAI05064 NM_014482 NP_055297
Function Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines. {ECO:0000269|PubMed:16049014, ECO:0000269|PubMed:17068149, ECO:0000269|PubMed:20608934}.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Detected in mammary epithelia (at protein level). {ECO:0000269|PubMed:20608934}.

BMP-10 - CL01247H01 from Elabscience

Species Human
Accession NM_014482.1

Human BMP-10 ORF clone(NM_014482.1) - CDCL182869 from Creative biogene

Species Human

Human BMP10 cDNA Clone(NM_014482.1) - CDFH001851 from Creative biogene

Species Human

Human BMP10 gene - orb91493 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human
Search more