BMP10

Gene Symbol	BMP10
Entrez Gene	27302
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	bone morphogenetic protein 10
Other Description	-
Swissprots	Q53R17 O95393 Q6NTE0
Accessions	AAY15075 EAW99863 O95393 AF101441 AAC77462 BC069080 AAH69080 BC101734 AAI01735 BC105063 AAI05064 NM_014482 NP_055297
Function	Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines. {ECO:0000269|PubMed:16049014, ECO:0000269|PubMed:17068149, ECO:0000269|PubMed:20608934}.
Subcellular Location	Secreted {ECO:0000250}.
Tissue Specificity	Detected in mammary epithelia (at protein level). {ECO:0000269|PubMed:20608934}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human BMP10 full length protein - ab176078 from Abcam Category Protein Prices $113.00, $316.00 Sizes 2 µg, 10 µg Source HEK 293 cells Species Human

Human BMP10 full length protein - ab153293 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human BMP10 protein fragment - ab153294 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BMP10 Antibody Blocking Peptide - LS-E4737 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BMP10 Antibody Blocking Peptide - LS-E17079 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BMP-10 Recombinant Protein - H00027302-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

BMP-10 Partial Recombinant Protein - H00027302-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human BMP-10 Protein - P4101 from Novus Biologicals Category Protein Prices $549.00 Sizes 20 µg Source E. coli Species Human

BMP-10 Protein - NBP1-99262 from Novus Biologicals Category Protein Prices $299.00 Sizes 20 µg Species Human

BMP-10 Protein - NBP1-99655 from Novus Biologicals Category Protein Species Human

BMP-10 Peptide - P0625 from Novus Biologicals Category Peptide Species Human

Bmp10-Antibody-N-term-Blocking-Peptide - BP1710a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BMP10 recombinant protein - GTX65420 from GeneTex Category Protein Prices $249.00 Sizes 20 μg Source E. coli Species Human

Recombinant Human BMP-10 - 2926-BP-025 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Asn317-Arg424

Recombinant Human BMP-10, CF - 2926-BP-025/CF from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Asn317-Arg424

Recombinant Human BMP-10 Propeptide, CF - 3956-BP-050 from R&D Systems Category Peptide Source Mouse myeloma cell line, NS0-derived

Human BMP10 protein - orb78519 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

BMP10 peptide - orb218491 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Bmp10 Blocking Peptide - 33R-4366 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BMP10 protein - 30R-2653 from Fitzgerald Category Protein Prices $265.00 Sizes 20 µg Source E.coli Species Human

BMP10 Blocking Peptide - abx063822 from Abbexa Category Peptide Species Human, Mouse, Rat

Human BMP10 Protein - abx065558 from Abbexa Category Protein Source E.coli Species Human

BMP10 - AR31107PU-N from Acris Antibodies Category Protein Prices $235.00 Sizes 10 µg Source HEK293 cells Species Human

BMP10 - AR31107PU-S from Acris Antibodies Category Protein Prices $135.00 Sizes 2 µg Source HEK293 cells Species Human

BMP10 - H00027302-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Search more