PRKAR2B

Gene Symbol PRKAR2B
Entrez Gene 5577
Alt Symbol PRKAR2, RII-BETA
Species Human
Gene Type protein-coding
Description protein kinase, cAMP-dependent, regulatory, type II, beta
Other Description H_RG363E19.2|WUGSC:H_RG363E19.2|cAMP-dependent protein kinase type II-beta regulatory chain|cAMP-dependent protein kinase type II-beta regulatory subunit
Swissprots A4D0R9 P31323
Accessions AAC08318 AAS07389 ABO15447 EAL24395 EAW83390 EAW83391 P31323 AK128639 BAG54705 AK291441 BAF84130 AL559918 AM392728 CAL37606 AM392771 CAL37649 AM393258 CAL38136 AM393700 CAL38576 BC014355 BC075800 AAH75800 BQ022817 CA405423 CF593944 M31158 AAA60099 XM_011516398 XP_011514700 XM_011516399 XP_011514701 NM_002736 NP_002727
Function Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21423175}. Cell membrane {ECO:0000269|PubMed:21423175}. Note=Colocalizes with PJA2 in the cytoplasm and at the cell membrane.
Tissue Specificity Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Top Pathways Apoptosis, Insulin signaling pathway

Human PKA 2 beta (regulatory subunit) protein fragment - ab152631 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE showing ab152631 stained with Coomassie Blue.

PRKAR2B Antibody Blocking Peptide - LS-E3750 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PRKAR2B Antibody Blocking Peptide - LS-E8645 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human PKA 2 beta Protein - H00005577-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

PRKAR2B-Antibody-Center-Blocking-Peptide - BP14960c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PKA-2-beta-PRKAR2B-Antibody-N-term-Blocking-peptide - BP7052a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PRKAR2B Blocking Peptide - abx063127 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine

PRKAR2B - H00005577-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PRKAR2B - H00005577-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

PRKAR2B fusion protein - ag11866 from Proteintech Group

Category Protein
Source E. coli-derived, T-HIS
Species Human
PRKAR2B fusion protein ag11866 SDS-PAGE

Recombinant Human PRKAR2B, His-tagged - PRKAR2B-1952H from Creative Biomart

Category Protein
Source E.coli
Species Human

PRKAR2B Blocking Peptide - CBP1933 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine

PKA IIβ reg (T109) Peptide - BS3253P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Recombinant Human cAMP-dependent protein kinase type II-beta regulatory subunit(PRKAR2B) - CSB-YP018698HU CSB-EP018698HU CSB-BP018698HU CSB-MP018698HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

PRKAR2B - TP309900 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
PRKAR2B

cAMP-dependent protein kinase type II-beta regulatory subunit (PRKAR2B), Recombinant Protein - MBS960364 from MyBioSource

Category Protein
Prices $1,190.00, $1,190.00, $1,410.00, $1,410.00, $1,920.00, $1,920.00, $2,385.00, $2,385.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

PKA 2 beta Recombinant Protein Antigen - NBP1-80879PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PRKAR2B Peptide, Human - M34GP12396H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

PRKAR2B peptide - orb217796 from Biorbyt

Category Peptide
Species Human, Mouse, Rat
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